| Product Number |
ARP45607_P050 |
| Product Page |
www.avivasysbio.com/rora-antibody-middle-region-arp45607-p050.html |
| Name |
RORA Antibody - middle region (ARP45607_P050) |
| Protein Size (# AA) |
548 amino acids |
| Molecular Weight |
62kDa |
| NCBI Gene Id |
6095 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
0.5 mg/ml |
| Gene Full Name |
RAR-related orphan receptor A |
| Alias Symbols |
ROR1, ROR2, ROR3, RZRA, NR1F1, IDDECA, RZR-ALPHA |
| Peptide Sequence |
Synthetic peptide located within the following region: PGEAEPLTPTYNISANGLTELHDDLSNYIDGHTPEGSKADSAVSSFYLDI |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reference |
Boukhtouche,F., (2006) J. Neurochem. 96 (6), 1778-1789 |
| Description of Target |
The protein encoded by RORA is a member of the NR1 subfamily of nuclear hormone receptors. It can bind as a monomer or as a homodimer to hormone response elements upstream of several genes to enhance the expression of those genes. The specific functions of this protein are not known, but it has been shown to interact with NM23-2, a nucleoside diphosphate kinase involved in organogenesis and differentiation, as well as with NM23-1, the product of a tumor metastasis suppressor candidate gene.The protein encoded by this gene is a member of the NR1 subfamily of nuclear hormone receptors. It can bind as a monomer or as a homodimer to hormone response elements upstream of several genes to enhance the expression of those genes. The specific functions of this protein are not known, but it has been shown to interact with NM23-2, a nucleoside diphosphate kinase involved in organogenesis and differentiation, as well as with NM23-1, the product of a tumor metastasis suppressor candidate gene. Four transcript variants encoding different isoforms have been described for this gene. |
| Protein Interactions |
GFAP; NSD1; NCOA1; PSMC5; SMARCD3; PTBP1; VPRBP; UBC; EZH2; DDB1; LMO3; NR0B1; ZXDC; PNRC2; COPS5; PNRC1; EIF3I; PROX1; LRIF1; RUVBL1; CEBPB; NCOA2; MED1; EP300; RORA; MYOD1; NME2; NME1; |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-RORA (ARP45607_P050) antibody |
| Blocking Peptide |
For anti-RORA (ARP45607_P050) antibody is Catalog # AAP45607 (Previous Catalog # AAPP11886) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the middle region of human RORA |
| Uniprot ID |
P35398-3 |
| Protein Name |
Nuclear receptor ROR-alpha |
| Protein Accession # |
NP_002934 |
| Purification |
Affinity Purified |
| Nucleotide Accession # |
NM_002943 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
RORA |
| Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Goat, Guinea Pig, Horse, Pig, Rabbit |
| Application |
WB, IHC |
| Predicted Homology Based on Immunogen Sequence |
Cow: 100%; Dog: 100%; Goat: 100%; Guinea Pig: 86%; Horse: 100%; Human: 100%; Mouse: 86%; Pig: 100%; Rabbit: 100%; Rat: 86% |
| Image 1 | Human Pineal Tissue
 | RORA antibody - middle region (ARP45607_P050)
Catalog Number: ARP45607_P050
Formalin Fixed Paraffin Embedded Tissue: Human Pineal Tissue
Observed Staining: Nucleus in Human Pineal Tissue
Primary Antibody Concentration: 1:100
Other Working Concentrations: 1/600
Secondary Antibody: Donkey anti-Rabbit-Cy3
Secondary Antibody Concentration: 1:200
Magnification: 20X
Exposure Time: 0.5 - 2.0 sec |
|
| Image 2 | Human HepG2
 | WB Suggested Anti-RORA Antibody Titration: 0.2-1 ug/ml
Positive Control: HepG2 cell lysate |
|
| Image 3 | Human THP-1 Whole Cell
 | Host: Rabbit
Target Name: RORA
Sample Tissue: Human THP-1 Whole Cell
Antibody Dilution: 1ug/ml |
|
