Product Number |
ARP44801_P050 |
Product Page |
www.avivasysbio.com/c1orf151-antibody-middle-region-arp44801-p050.html |
Name |
C1orf151 Antibody - middle region (ARP44801_P050) |
Protein Size (# AA) |
78 amino acids |
Molecular Weight |
9 kDa |
NCBI Gene Id |
440574 |
Host |
Rabbit |
Clonality |
Polyclonal |
Concentration |
0.5 mg/ml |
Gene Full Name |
Mitochondrial inner membrane organizing system 1 |
Description |
|
Alias Symbols |
MIO10, Mic10, MINOS1, C1orf151 |
Peptide Sequence |
Synthetic peptide located within the following region: IVFSLTFFKRRMWPLAFGSGMGLGMAYSNCQHDFQAPYLLHGKYVKEQEQ |
Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reference |
Gregory,S.G., (2006) Nature 441 (7091), 315-321 |
Description of Target |
The exact function of C1orf151 remains unknown. |
Protein Interactions |
MIA3; GSTK1; IBA57; RDH13; COA7; DNAJC11; CHCHD3; RMDN1; SAMM50; ACOT9; IMMT; TUBGCP2; MTHFD2; MTX2; TUBG1; MAPK1; MTX1; HSPA9; GDI1; FECH; ACSL4; C1QBP; |
Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
Enhanced Validation |
|
Datasheets/Manuals |
Printable datasheet for anti-MINOS1 (ARP44801_P050) antibody |
Blocking Peptide |
For anti-MINOS1 (ARP44801_P050) antibody is Catalog # AAP44801 (Previous Catalog # AAPP12277) |
Immunogen |
The immunogen is a synthetic peptide directed towards the middle region of human C1orf151 |
Uniprot ID |
Q5TGZ0 |
Protein Name |
Mitochondrial inner membrane organizing system protein 1 |
Publications |
A novel homozygous variant in MICOS13/QIL1 causes hepato-encephalopathy with mitochondrial DNA depletion syndrome. Mol Genet Genomic Med. 8, e1427 (2020). 32749073
Accessory subunits are integral for assembly and function of human mitochondrial complex I. Nature. 538, 123-126 (2016). 27626371
Dissecting the Roles of Mitochondrial Complex I Intermediate Assembly Complex Factors in the Biogenesis of Complex I. Cell Rep. 31, 107541 (2020). 32320651
FAM92A1 is a BAR domain protein required for mitochondrial ultrastructure and function. J Cell Biol. 218, 97-111 (2019). 30404948
Jans, D. C. et al. STED super-resolution microscopy reveals an array of MINOS clusters along human mitochondria. Proc. Natl. Acad. Sci. U. S. A. 110, 8936-41 (2013). 23676277
Mitochondrial hepato-encephalopathy due to deficiency of QIL1/MIC13 (C19orf70), a MICOS complex subunit. Eur J Hum Genet. 24, 1778-1782 (2016). 27485409 |
Protein Accession # |
NP_001027535 |
Purification |
Affinity Purified |
Nucleotide Accession # |
NM_001032363 |
Tested Species Reactivity |
Human |
Gene Symbol |
MINOS1 |
Predicted Species Reactivity |
Human, Mouse, Rat, Dog, Guinea Pig, Horse, Rabbit |
Application |
WB |
Predicted Homology Based on Immunogen Sequence |
Dog: 100%; Guinea Pig: 100%; Horse: 93%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100% |
Image 1 | Human Liver Tumor
| Host: Rabbit Target Name: MINOS1 Sample Tissue: Human Liver Tumor Antibody Dilution: 1ug/ml |
|
Image 2 | Human COLO205 Whole Cell
| Host: Rabbit Target Name: MINOS1 Sample Tissue: Human COLO205 Whole Cell Antibody Dilution: 1ug/ml |
|
Image 3 | Western Blot
| 25 ug of the indicated Human whole cell extracts was loaded onto a 10-20% SDS-PAGE gel. 3 ug/mL of the antibody was used in this experiment. Recommended dilution for this antibody is 1-3 ug/mL. |
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