| Product Number |
ARP44277_P050 |
| Product Page |
www.avivasysbio.com/ext2-antibody-n-terminal-region-arp44277-p050.html |
| Name |
EXT2 Antibody - N-terminal region (ARP44277_P050) |
| Protein Size (# AA) |
718 amino acids |
| Molecular Weight |
82kDa |
| NCBI Gene Id |
2132 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
0.5 mg/ml |
| Gene Full Name |
Exostosin 2 |
| Description |
|
| Alias Symbols |
SOTV, SSMS |
| Peptide Sequence |
Synthetic peptide located within the following region: NELLMAISDSDYYTDDINRACLFVPSIDVLNQNTLRIKETAQAMAQLSRW |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reference |
Leube,B., (2008) Genet. Test. 12 (1), 129-133 |
| Description of Target |
EXT2 is one of two glycosyltransferases involved in the chain elongation step of heparan sulfate biosynthesis.This gene encodes one of two glycosyltransferases involved in the chain elongation step of heparan sulfate biosynthesis. Mutations in this gene cause the type II form of multiple exostoses. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. |
| Protein Interactions |
UBC; GSKIP; SLC22A2; CDKN1A; ANXA7; TK1; SMN1; PFDN1; GALNT5; TRAP1; EXT2; EXT1; CLEC2L; CRB1; HYOU1; STK16; TCEB1; SNCG; RPS29; HNF4A; FABP4; CNTF; |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-EXT2 (ARP44277_P050) antibody |
| Blocking Peptide |
For anti-EXT2 (ARP44277_P050) antibody is Catalog # AAP44277 (Previous Catalog # AAPP26654) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the N terminal region of human EXT2 |
| Uniprot ID |
Q93063 |
| Protein Name |
Exostosin-2 |
| Publications |
Oocyte Cytoplasmic Gas6 and Heparan Sulfate (HS) are Required to Establish the Open Chromatin State in Nuclei During Remodeling and Reprogramming. Cell Physiol Biochem. 45, 37-53 (2018). 29316553 |
| Sample Type Confirmation |
EXT2 is supported by BioGPS gene expression data to be expressed in HeLa |
| Protein Accession # |
NP_000392 |
| Purification |
Affinity Purified |
| Nucleotide Accession # |
NM_000401 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
EXT2 |
| Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit, Zebrafish |
| Application |
WB, IHC |
| Predicted Homology Based on Immunogen Sequence |
Cow: 86%; Dog: 100%; Guinea Pig: 86%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 93%; Rabbit: 100%; Rat: 93%; Zebrafish: 79% |
| Image 1 | Human 721_B
 | WB Suggested Anti-EXT2 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:312500
Positive Control: 721_B cell lysate |
|
| Image 2 | Human heart
 | Rabbit Anti-EXT2 Antibody
Catalog Number: ARP44277_P050
Formalin Fixed Paraffin Embedded Tissue: Human heart Tissue
Observed Staining: Cytoplasmic
Primary Antibody Concentration: N/A
Other Working Concentrations: 1:600
Secondary Antibody: Donkey anti-Rabbit-Cy3
Secondary Antibody Concentration: 1:200
Magnification: 20X
Exposure Time: 0.5 - 2.0 sec |
|
| Image 3 | Human Hela
 | Host: Rabbit
Target Name: EXT2
Sample Type: Human Hela
Antibody Dilution: 1.0ug/mlEXT2 is supported by BioGPS gene expression data to be expressed in HeLa |
|
