C8B Antibody - middle region : FITC (ARP44210_P050-FITC)

Data Sheet
 
Product Number ARP44210_P050-FITC
Product Page www.avivasysbio.com/c8b-antibody-middle-region-fitc-arp44210-p050-fitc.html
Name C8B Antibody - middle region : FITC (ARP44210_P050-FITC)
Protein Size (# AA) 591 amino acids
Molecular Weight 61kDa
Conjugation FITC: Fluorescein Isothiocyanate
NCBI Gene Id 732
Host Rabbit
Clonality Polyclonal
Concentration 0.5 mg/ml
Gene Full Name Complement component 8, beta polypeptide
Alias Symbols C82
Peptide Sequence Synthetic peptide located within the following region: WKPGSSGPGSTGSWNSGSSGTGSTGNQNPGSPRPGSTGTWNPGSSERGSA
Product Format Liquid. Purified antibody supplied in 1x PBS buffer.
Reference Gregory,S.G., (2006) Nature 441 (7091), 315-321
Description of Target C8 beta is one of the three subunits that comprise the component 8 (C8) of the complement system. C8 participates in the formation of Membrane Attack Complex that results in the lysis of cells. Patients with C8B deficiency are prone to bacteria infection.C8 beta is one of the three subunits that comprise the component 8 (C8) of the complement system. C8 participates in the formation of Membrane Attack Complex that results in the lysis of cells. Patients with C8B deficiency are prone to bacteria infection. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Protein Interactions CLU; C8A; C5;
Reconstitution and Storage All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil). Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Datasheets/Manuals Printable datasheet for anti-C8B (ARP44210_P050-FITC) antibody
Additional Information IHC Information: Fetal liver cell lysate. Antibody concentration: 0.5 ug/ml. Gel concentration: 12%.
Blocking Peptide For anti-C8B (ARP44210_P050-FITC) antibody is Catalog # AAP44210 (Previous Catalog # AAPP11986)
Immunogen The immunogen is a synthetic peptide directed towards the middle region of human C8B
Uniprot ID P07358
Protein Name Complement component C8 beta chain
Protein Accession # NP_000057
Purification Affinity Purified
Nucleotide Accession # NM_000066
Gene Symbol C8B
Predicted Species Reactivity Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit
Application IHC, WB
Predicted Homology Based on Immunogen Sequence Cow: 100%; Dog: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 93%; Rabbit: 93%; Rat: 100%
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