| Product Number |
ARP43850_P050 |
| Product Page |
www.avivasysbio.com/slc25a11-antibody-c-terminal-region-arp43850-p050.html |
| Name |
SLC25A11 Antibody - C-terminal region (ARP43850_P050) |
| Protein Size (# AA) |
314 amino acids |
| Molecular Weight |
34kDa |
| NCBI Gene Id |
8402 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
0.5 mg/ml |
| Gene Full Name |
Solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11 |
| Alias Symbols |
OGC, PGL6, SLC20A4 |
| Peptide Sequence |
Synthetic peptide located within the following region: DGKPEYKNGLDVLFKVVRYEGFFSLWKGFTPYYARLGPHTVLTFIFLEQM |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reference |
Kabe,Y., (2006) J. Biol. Chem. 281 (42), 31729-31735 |
| Description of Target |
SLC25A11 catalyzes the transport of 2-oxoglutarate across the inner mitochondrial membrane in an electroneutral exchange for malate or other dicarboxylic acids, and plays an important role in several metabolic processes, including the malate-aspartate shuttle, the oxoglutarate/isocitrate shuttle, in gluconeogenesis from lactate, and in nitrogen metabolism. |
| Protein Interactions |
RAPGEF2; UBC; SUMO2; STAU1; SUZ12; RNF2; BMI1; FBXO6; FBXO46; FBXW4; ADRB2; CLN5; CLN3; MMS19; UBL4A; MDC1; ECT2; FLOT1; HDAC5; MYC; ICT1; CEBPA; CAMKK2; BABAM1; SLC25A11; COPA; CDKN1A; |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-SLC25A11 (ARP43850_P050) antibody |
| Blocking Peptide |
For anti-SLC25A11 (ARP43850_P050) antibody is Catalog # AAP43850 (Previous Catalog # AAPS14311) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the C terminal region of human SLC25A11 |
| Uniprot ID |
Q02978 |
| Protein Name |
Mitochondrial 2-oxoglutarate/malate carrier protein |
| Protein Accession # |
NP_003553 |
| Purification |
Affinity Purified |
| Nucleotide Accession # |
NM_003562 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
SLC25A11 |
| Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Sheep, Zebrafish |
| Application |
WB, IHC |
| Predicted Homology Based on Immunogen Sequence |
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Sheep: 100%; Zebrafish: 100% |
| Image 1 | Transfected 293T
 | WB Suggested Anti-SLC25A11 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:62500
Positive Control: Transfected 293T |
|
| Image 2 | Human Liver Tissue
 | SLC25A11 antibody - C-terminal region (ARP43850_P050)
Catalog Number: ARP43850_P050
Formalin Fixed Paraffin Embedded Tissue: Human Liver Tissue
Observed Staining: Cytoplasm in mitochondria of hepatocytes
Primary Antibody Concentration: 1:100
Secondary Antibody: Donkey anti-Rabbit-Cy3
Secondary Antibody Concentration: 1:200
Magnification: 20X
Exposure Time: 0.5 - 2.0 sec |
|
