SP1 Antibody - middle region (ARP43585_P050)

Data Sheet
 
Product Number ARP43585_P050
Product Page www.avivasysbio.com/sp1-antibody-middle-region-arp43585-p050.html
Name SP1 Antibody - middle region (ARP43585_P050)
Protein Size (# AA) 785 amino acids
Molecular Weight 81kDa
Conjugation Unconjugated
NCBI Gene Id 6667
Host Rabbit
Clonality Polyclonal
Concentration 0.5 mg/ml
Gene Full Name Sp1 transcription factor
Alias Symbols -
Peptide Sequence Synthetic peptide located within the following region: TLTPIASAASIPAGTVTVNAAQLSSMPGLQTINLSALGTSGIQVHPIQGL
Product Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reference Yoshimura,M., (2008) Biochem. Biophys. Res. Commun. 369 (3), 939-942
Description of Target SP1 belongs to the Sp1 C2H2-type zinc-finger protein family. It contains 3 C2H2-type zinc fingers. SP1 binds to GC box promoters elements and selectively activates mRNA synthesis from genes that contain functional recognition sites. It can interact with G/C-rich motifs from serotonin receptor promoter.
Protein Interactions JUN; UBC; HIC1; HDAC1; SP3; TP53; CTNNB1; ARHGAP21; SENP6; C3orf17; USP39; FOXM1; ESR1; DDX5; KIF1A; PPIG; TPI1; TFAP2A; NAP1L1; HDAC2; NUP62; MYC; HIF1A; POU2F1; SMAD3; DDX3X; TBP; SP1; RBL1; Taf4; tat; ESR2; VHL; YY1; CASP7; CASP6; CASP3; HTT; BRCA1; MA
Reconstitution and Storage For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Datasheets/Manuals Printable datasheet for anti-SP1 (ARP43585_P050) antibody
Blocking Peptide For anti-SP1 (ARP43585_P050) antibody is Catalog # AAP43585 (Previous Catalog # AAPS13612)
Immunogen The immunogen is a synthetic peptide directed towards the middle region of human SP1
Uniprot ID P08047
Protein Name Transcription factor Sp1
Protein Accession # NP_612482
Purification Affinity Purified
Nucleotide Accession # NM_138473
Tested Species Reactivity Human
Gene Symbol SP1
Predicted Species Reactivity Human, Mouse, Rat, Cow, Dog, Goat, Guinea Pig, Pig, Rabbit
Application WB
Predicted Homology Based on Immunogen Sequence Cow: 100%; Dog: 100%; Goat: 100%; Guinea Pig: 87%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%
Image 1
Human Muscle
WB Suggested Anti-SP1 Antibody Titration: 0.2-1 ug/ml
Positive Control: Human Muscle
 

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