Product Number |
ARP43285_P050 |
Product Page |
www.avivasysbio.com/dtx2-antibody-c-terminal-region-arp43285-p050.html |
Name |
DTX2 Antibody - C-terminal region (ARP43285_P050) |
Protein Size (# AA) |
575 amino acids |
Molecular Weight |
62kDa |
NCBI Gene Id |
113878 |
Host |
Rabbit |
Clonality |
Polyclonal |
Concentration |
0.5 mg/ml |
Gene Full Name |
Deltex homolog 2 (Drosophila) |
Alias Symbols |
RNF58 |
Peptide Sequence |
Synthetic peptide located within the following region: EDCGTILIVYSIPHGIQGPEHPNPGKPFTARGFPRQCYLPDNAQGRKVLE |
Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Description of Target |
DTX2 is a regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. DTX2 probably acts both as a positive and negative regulator of Notch, depending on the developmental and cell context and mediates the antineural activity of Notch, possibly by inhibiting the transcriptional activation mediated by MATCH1. It also functions as an ubiquitin ligase protein in vitro, suggesting that it may regulate the Notch pathway via some ubiquitin ligase activity. |
Protein Interactions |
KRTAP26-1; RFX6; KLC3; GLYCTK; DTX2; RIMBP3; C1orf94; NCALD; PLEKHF2; TRIM54; EIF4ENIF1; ALKBH4; UBE2D4; HPCAL4; SPG21; SEC22A; SPAG8; STX12; NCS1; FAM168A; RBPMS; SEC23B; ABHD16A; VSNL1; SUMO1; UBE2D3; UBE2D1; UBC; TRIP6; QARS; HDC; GOLGA2; FHL2; ARNT2; |
Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
Datasheets/Manuals |
Printable datasheet for anti-DTX2 (ARP43285_P050) antibody |
Blocking Peptide |
For anti-DTX2 (ARP43285_P050) antibody is Catalog # AAP43285 (Previous Catalog # AAPP11360) |
Immunogen |
The immunogen is a synthetic peptide directed towards the C terminal region of human DTX2 |
Uniprot ID |
Q6XM87 |
Protein Name |
Probable E3 ubiquitin-protein ligase DTX2 |
Protein Accession # |
NP_001096066 |
Purification |
Affinity Purified |
Nucleotide Accession # |
NM_001102596 |
Tested Species Reactivity |
Human |
Gene Symbol |
DTX2 |
Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Goat, Guinea Pig, Horse, Rabbit, Zebrafish |
Application |
WB |
Predicted Homology Based on Immunogen Sequence |
Cow: 100%; Dog: 100%; Goat: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 93% |
Image 1 | Human HepG2
| WB Suggested Anti-DTX2 Antibody Titration: 0.2-1 ug/ml Positive Control: HepG2 cell lysate |
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