Product Number |
ARP43233_P050 |
Product Page |
www.avivasysbio.com/march5-antibody-c-terminal-region-arp43233-p050.html |
Name |
MARCH5 Antibody - C-terminal region (ARP43233_P050) |
Protein Size (# AA) |
278 amino acids |
Molecular Weight |
31kDa |
NCBI Gene Id |
54708 |
Host |
Rabbit |
Clonality |
Polyclonal |
Concentration |
0.5 mg/ml |
Gene Full Name |
Membrane-associated ring finger (C3HC4) 5 |
Alias Symbols |
MITOL, MARCH5, RNF153, MARCH-V |
Peptide Sequence |
Synthetic peptide located within the following region: VNSNLQRTILGGIAFVAIKGAFKVYFKQQQYLRQAHRKILNYPEQEEA |
Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reference |
Karbowski,M., (2007) J. Cell Biol. 178 (1), 71-84 |
Description of Target |
MARCH5 is an ubiquitin ligase of the mitochondrial outer membrane that plays a role in the control of mitochondrial morphology by regulating mitofusin-2 (MFN2) and DRP1 (DNM1L).MARCH5 is a ubiquitin ligase of the mitochondrial outer membrane that plays a role in the control of mitochondrial morphology by regulating mitofusin-2 (MFN2; MIM 608507) and DRP1 (DNM1L; MIM 603850) (Nakamura et al., 2006 [PubMed 16936636]).[supplied by OMIM]. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-1502 AK000452.1 3-1504 1503-1863 BC015480.1 1463-1823 1864-1901 BE393612.1 438-475 1902-3713 BC015480.1 1852-3663 3714-3941 BC015480.1 3669-3896 |
Protein Interactions |
FATE1; UBE2W; UBC; DNM1L; MFN2; UBE2E1; FIS1; UBE2E3; MFN1; PARK2; MARCH5; CCNB1; UBE2D3; UBE2D2; UBE2D1; MAP1B; KIAA0368; SOD1; MAVS; TANK; TRAF6; AKTIP; UBE2T; UBE2N; UBE2I; UTRN; |
Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
Datasheets/Manuals |
Printable datasheet for anti-MARCH5 (ARP43233_P050) antibody |
Blocking Peptide |
For anti-MARCH5 (ARP43233_P050) antibody is Catalog # AAP43233 (Previous Catalog # AAPP11308) |
Immunogen |
The immunogen is a synthetic peptide directed towards the C terminal region of human MARCH5 |
Uniprot ID |
Q9NX47 |
Protein Name |
E3 ubiquitin-protein ligase MARCH5 |
Protein Accession # |
NP_060294 |
Purification |
Affinity Purified |
Nucleotide Accession # |
NM_017824 |
Tested Species Reactivity |
Human |
Gene Symbol |
MARCH5 |
Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish |
Application |
WB |
Predicted Homology Based on Immunogen Sequence |
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100% |
Image 1 | Human Fetal Kidney
| Host: Rabbit Target Name: MARCH5 Sample Type: Human Fetal Kidney Antibody Dilution: 1.0ug/ml |
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