| Product Number |
ARP43117_P050 |
| Product Page |
www.avivasysbio.com/fbxo25-antibody-n-terminal-region-arp43117-p050.html |
| Name |
FBXO25 Antibody - N-terminal region (ARP43117_P050) |
| Protein Size (# AA) |
291 amino acids |
| Molecular Weight |
34kDa |
| NCBI Gene Id |
26260 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
0.5 mg/ml |
| Gene Full Name |
F-box protein 25 |
| Alias Symbols |
FBX25 |
| Peptide Sequence |
Synthetic peptide located within the following region: LGEAFNRLDFSSAIQDIRRFNYVVKLLQLIAKSQLTSLSGVAQKNYFNIL |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reference |
Hagens,O., (2006) Biochim. Biophys. Acta 1760 (1), 110-118 |
| Description of Target |
FBXO25 is a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein belongs to the Fbxs class. Three alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. Three alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. |
| Protein Interactions |
SYTL2; ING3; TMA7; HP1BP3; ADRBK1; PRRG1; PRKG2; PRKCA; PPP1R8; PPID; PDGFRA; PCK1; ODF2; KRT8; KDR; IRS1; DNAJB2; HIP1; GTF2B; FKBP3; ELK1; EGFR; DCX; EID3; PRR15; APLF; TCEANC; WDSUB1; TRUB1; TCEAL2; TCP10L; ANKRD13A; C7orf50; RHBDD1; NSRP1; RABEP2; C11 |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-FBXO25 (ARP43117_P050) antibody |
| Blocking Peptide |
For anti-FBXO25 (ARP43117_P050) antibody is Catalog # AAP43117 (Previous Catalog # AAPP25086) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the N terminal region of human FBXO25 |
| Uniprot ID |
Q8TCJ0 |
| Protein Name |
F-box only protein 25 |
| Protein Accession # |
NP_036305 |
| Purification |
Affinity Purified |
| Nucleotide Accession # |
NM_012173 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
FBXO25 |
| Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit, Zebrafish |
| Application |
WB |
| Predicted Homology Based on Immunogen Sequence |
Cow: 100%; Dog: 93%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 93%; Pig: 100%; Rabbit: 93%; Rat: 93%; Zebrafish: 93% |
| Image 1 | Human Heart
 | WB Suggested Anti-FBXO25 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:312500
Positive Control: Human heart |
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