TJP2 Antibody - C-terminal region (ARP42942_P050)

Data Sheet
 
Product Number ARP42942_P050
Product Page www.avivasysbio.com/tjp2-antibody-c-terminal-region-arp42942-p050.html
Name TJP2 Antibody - C-terminal region (ARP42942_P050)
Protein Size (# AA) 1043 amino acids
Molecular Weight 118kDa
NCBI Gene Id 9414
Host Rabbit
Clonality Polyclonal
Concentration 0.5 mg/ml
Gene Full Name Tight junction protein 2 (zona occludens 2)
Alias Symbols ZO2, X104, FHCA1, PFIC4, DFNA51, DUP9q21.11, C9DUPq21.11
Peptide Sequence Synthetic peptide located within the following region: EPQKAPSRPYQDTRGSYGSDAEEEEYRQQLSEHSKRGYYGQSARYRDTEL
Product Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reference Bel (2008) Hum. Genet. 123 (3), 267-272
Description of Target Tight junction proteins (TJPs) belong to a family of membrane-associated guanylate kinase (MAGUK) homologs that are involved in the organization of epithelial and endothelial intercellular junctions. TJPs bind to the cytoplasmic C termini of junctional transmembrane proteins and link them to the actin cytoskeleton.Tight junction proteins (TJPs) belong to a family of membrane-associated guanylate kinase (MAGUK) homologs that are involved in the organization of epithelial and endothelial intercellular junctions. TJPs bind to the cytoplasmic C termini of junctional transmembrane proteins and link them to the actin cytoskeleton.[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-260 BC027592.1 10-269 261-1975 BC027592.1 270-1984 1976-2543 L27476.1 1855-2422 2544-3142 BC028426.1 2440-3038 3143-4160 L27476.1 3467-4484 4161-4177 BC028426.1 4056-4072
Protein Interactions SNAI2; UBC; KCMF1; PGAM5; KIAA1671; LATS2; YAP1; KIF14; LATS1; TJP1; SRPK2; SRPK1; PLOD1; CDK6; ZMYM3; THOC5; UBN1; CLDN2; SIRT7; SSTR3; YWHAZ; YWHAG; YWHAB; OCLN; SRRM2; KBTBD7; RAE1; CGN; SCRIB; CLDN1; SAFB; SH3KBP1; EPB41; CTNNA1; HGS; YWHAQ; TRAF6; SF
Reconstitution and Storage For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Datasheets/Manuals Printable datasheet for anti-TJP2 (ARP42942_P050) antibody
Blocking Peptide For anti-TJP2 (ARP42942_P050) antibody is Catalog # AAP42942 (Previous Catalog # AAPS13205)
Immunogen The immunogen is a synthetic peptide directed towards the C terminal region of human TJP2
Uniprot ID A2A3H9
Protein Name Tight junction protein ZO-2
Protein Accession # NP_963923
Purification Affinity Purified
Nucleotide Accession # NM_201629
Tested Species Reactivity Human
Gene Symbol TJP2
Predicted Species Reactivity Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish
Application WB
Predicted Homology Based on Immunogen Sequence Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 93%; Human: 100%; Mouse: 93%; Rabbit: 100%; Rat: 100%; Zebrafish: 82%
Image 1
HepG2 Cell Lysate, 293T Cell Lysate
Host: Rabbit
Target: TJP2
Positive control (+): HepG2 Cell Lysate (HG)
Negative control (-): 293T Cell Lysate (2T)
Antibody concentration: 1ug/ml
Image 2
Human Jurkat
WB Suggested Anti-TJP2 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:62500
Positive Control: Jurkat cell lysate
 

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