| Product Number |
ARP42736_P050 |
| Product Page |
www.avivasysbio.com/acly-antibody-middle-region-arp42736-p050.html |
| Name |
ACLY Antibody - middle region (ARP42736_P050) |
| Protein Size (# AA) |
1101 amino acids |
| Molecular Weight |
121kDa |
| NCBI Gene Id |
47 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
0.5 mg/ml |
| Gene Full Name |
ATP citrate lyase |
| Alias Symbols |
ACL, ATPCL, CLATP |
| Peptide Sequence |
Synthetic peptide located within the following region: SRTASFSESRADEVAPAKKAKPAMPQDSVPSPRSLQGKSTTLFSRHTKAI |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reference |
0 |
| Description of Target |
ATP citrate lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. The enzyme is a tetramer (relative molecular weight approximately 440,000) of apparently identical subunits. It catalyzes the formation of acety |
| Protein Interactions |
UBC; UBR4; SIRT2; HUWE1; ISG15; KAT2B; SUMO2; SUMO3; STAU1; SUMO1; NEDD8; MDM2; ASB15; WWOX; TRIM25; MAGED2; BAG3; PPP6C; NCL; MCM6; MCM2; KPNA4; KPNA2; PRMT1; CDKN2A; SRRT; UBD; FN1; APP; SHC1; CUL3; CAND1; CUL2; SIRT7; UL27; HDAC5; TERF2; TERF1; GSK3B; |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-ACLY (ARP42736_P050) antibody |
| Blocking Peptide |
For anti-ACLY (ARP42736_P050) antibody is Catalog # AAP42736 (Previous Catalog # AAPP24960) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the middle region of human ACLY |
| Uniprot ID |
P53396 |
| Protein Name |
ATP-citrate synthase |
| Publications |
The contribution of the citrate pathway to oxidative stress in Down syndrome. Immunology. 149, 423-431 (2016). 27502741 |
| Sample Type Confirmation |
ACLY is strongly supported by BioGPS gene expression data to be expressed in ACHN |
| Protein Accession # |
NP_001087 |
| Purification |
Affinity Purified |
| Nucleotide Accession # |
NM_001096 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
ACLY |
| Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit, Sheep, Zebrafish |
| Application |
WB |
| Predicted Homology Based on Immunogen Sequence |
Cow: 92%; Dog: 93%; Guinea Pig: 86%; Horse: 92%; Human: 100%; Mouse: 93%; Pig: 93%; Rabbit: 100%; Rat: 93%; Sheep: 92%; Zebrafish: 79% |
| Image 1 | Human ACHN
 | WB Suggested Anti-ACLY Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:312500
Positive Control: ACHN cell lysateACLY is strongly supported by BioGPS gene expression data to be expressed in Human ACHN cells |
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