HP Antibody - N-terminal region (ARP42218_P050)

Data Sheet
Product Number ARP42218_P050
Product Page www.avivasysbio.com/hp-antibody-n-terminal-region-arp42218-p050.html
Name HP Antibody - N-terminal region (ARP42218_P050)
Protein Size (# AA) 406 amino acids
Molecular Weight 60 kDa
NCBI Gene Id 3240
Host Rabbit
Clonality Polyclonal
Concentration 0.5 mg/ml
Gene Full Name Haptoglobin
Alias Symbols BP, HPA1S, HP2ALPHA2
Peptide Sequence Synthetic peptide located within the following region: MSALGAVIALLLWGQLFAVDSGNDVTDIADDGCPKPPEIAHGYVEHSVRY
Product Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reference Borsody,M., (2006) Neurology 66 (5), 634-640
Description of Target Haptoglobin combines with free plasma hemoglobin, preventing loss of iron through the kidneys and protecting the kidneys from damage by hemoglobin, while making the hemoglobin accessible to degradative enzymes.
Protein Interactions GADD45G; LAMC3; MVP; WASL; TP63; TGM2; TBL1X; RPL11; SMAD3; ALB; VKORC1; ATP7B; ELAVL1; RBBP6; GRB2; MIS12; C1RL; CD163; ADAMTS4; ITGB2; HBB; ITGAM; CD22;
Reconstitution and Storage For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Enhanced Validation
Relative Expression (Western Blot) Avivasheild
Datasheets/Manuals Printable datasheet for anti-HP (ARP42218_P050) antibody
Blocking Peptide For anti-HP (ARP42218_P050) antibody is Catalog # AAP42218 (Previous Catalog # AAPP24641)
Immunogen The immunogen is a synthetic peptide directed towards the N terminal region of human HP
Uniprot ID P00738
Protein Name Haptoglobin
Protein Accession # NP_005134
Purification Affinity Purified
Nucleotide Accession # NM_005143
Tested Species Reactivity Human
Gene Symbol HP
Predicted Species Reactivity Human, Mouse, Rat, Dog, Guinea Pig, Horse, Pig, Rabbit
Application WB, IHC
Predicted Homology Based on Immunogen Sequence Dog: 77%; Guinea Pig: 77%; Horse: 85%; Human: 100%; Mouse: 92%; Pig: 85%; Rabbit: 92%; Rat: 92%
Image 1
Human Liver Tissue
HP (haptoglobin)antibody - N-terminal region (ARP42218_P050)
Catalog Number: ARP42218_P050
Formalin Fixed Paraffin Embedded Tissue: Human Liver Tissue
Observed Staining: Cytoplasm in hepatocytes
Primary Antibody Concentration: 1:100
Secondary Antibody: Donkey anti-Rabbit-Cy3
Secondary Antibody Concentration: 1:200
Magnification: 20X
Exposure Time: 0.5 - 2.0 sec
Image 2

25 ug of the indicated Human whole cell or tissue extracts was loaded onto a 12% SDS-PAGE gel. 1 ug/mL of the antibody was used in this experiment.

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