Product Number |
ARP42218_P050 |
Product Page |
www.avivasysbio.com/hp-antibody-n-terminal-region-arp42218-p050.html |
Name |
HP Antibody - N-terminal region (ARP42218_P050) |
Protein Size (# AA) |
406 amino acids |
Molecular Weight |
60 kDa |
NCBI Gene Id |
3240 |
Host |
Rabbit |
Clonality |
Polyclonal |
Concentration |
0.5 mg/ml |
Gene Full Name |
Haptoglobin |
Alias Symbols |
BP, HPA1S, HP2ALPHA2 |
Peptide Sequence |
Synthetic peptide located within the following region: MSALGAVIALLLWGQLFAVDSGNDVTDIADDGCPKPPEIAHGYVEHSVRY |
Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reference |
Borsody,M., (2006) Neurology 66 (5), 634-640 |
Description of Target |
Haptoglobin combines with free plasma hemoglobin, preventing loss of iron through the kidneys and protecting the kidneys from damage by hemoglobin, while making the hemoglobin accessible to degradative enzymes. |
Protein Interactions |
GADD45G; LAMC3; MVP; WASL; TP63; TGM2; TBL1X; RPL11; SMAD3; ALB; VKORC1; ATP7B; ELAVL1; RBBP6; GRB2; MIS12; C1RL; CD163; ADAMTS4; ITGB2; HBB; ITGAM; CD22; |
Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
Enhanced Validation |
Relative Expression (Western Blot) |
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Datasheets/Manuals |
Printable datasheet for anti-HP (ARP42218_P050) antibody |
Blocking Peptide |
For anti-HP (ARP42218_P050) antibody is Catalog # AAP42218 (Previous Catalog # AAPP24641) |
Immunogen |
The immunogen is a synthetic peptide directed towards the N terminal region of human HP |
Uniprot ID |
P00738 |
Protein Name |
Haptoglobin |
Protein Accession # |
NP_005134 |
Purification |
Affinity Purified |
Nucleotide Accession # |
NM_005143 |
Tested Species Reactivity |
Human |
Gene Symbol |
HP |
Predicted Species Reactivity |
Human, Mouse, Rat, Dog, Guinea Pig, Horse, Pig, Rabbit |
Application |
WB, IHC |
Predicted Homology Based on Immunogen Sequence |
Dog: 77%; Guinea Pig: 77%; Horse: 85%; Human: 100%; Mouse: 92%; Pig: 85%; Rabbit: 92%; Rat: 92% |
Image 1 | Human Liver Tissue
| HP (haptoglobin)antibody - N-terminal region (ARP42218_P050)
Catalog Number: ARP42218_P050
Formalin Fixed Paraffin Embedded Tissue: Human Liver Tissue
Observed Staining: Cytoplasm in hepatocytes
Primary Antibody Concentration: 1:100
Secondary Antibody: Donkey anti-Rabbit-Cy3
Secondary Antibody Concentration: 1:200
Magnification: 20X
Exposure Time: 0.5 - 2.0 sec |
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Image 2 |
| 25 ug of the indicated Human whole cell or tissue extracts was loaded onto a 12% SDS-PAGE gel. 1 ug/mL of the antibody was used in this experiment. |
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