| Product Number |
ARP42041_P050 |
| Product Page |
www.avivasysbio.com/mmp3-antibody-middle-region-arp42041-p050.html |
| Name |
MMP3 Antibody - middle region (ARP42041_P050) |
| Protein Size (# AA) |
477 amino acids |
| Molecular Weight |
43kDa |
| NCBI Gene Id |
4314 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
0.5 mg/ml |
| Gene Full Name |
Matrix metallopeptidase 3 (stromelysin 1, progelatinase) |
| Alias Symbols |
SL-1, STMY, STR1, CHDS6, MMP-3, STMY1 |
| Peptide Sequence |
Synthetic peptide located within the following region: SFAVREHGDFYPFDGPGNVLAHAYAPGPGINGDAHFDDDEQWTKDTTGTN |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Description of Target |
MMP3 can degrade fibronectin, laminin, gelatins of type I, III, IV, and V; collagens III, IV, X, and IX, and cartilage proteoglycans. MMP3 activates procollagenase. |
| Protein Interactions |
MEOX2; SPOCK3; SPOCK1; TNFSF11; CCL8; CCL13; BCAN; TIMP1; TIMP3; MMP3; SERPINE1; PLG; SPP1; CCL7; CCL2; ACAN; IGFBP3; DCN; HAPLN1; |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-MMP3 (ARP42041_P050) antibody |
| Blocking Peptide |
For anti-MMP3 (ARP42041_P050) antibody is Catalog # AAP42041 (Previous Catalog # AAPP24522) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the middle region of human MMP3 |
| Uniprot ID |
P28862 |
| Protein Name |
Stromelysin-1 |
| Protein Accession # |
NP_002413 |
| Purification |
Affinity Purified |
| Nucleotide Accession # |
NM_002422 |
| Tested Species Reactivity |
Human, Horse |
| Gene Symbol |
MMP3 |
| Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit, Sheep, Zebrafish |
| Application |
IHC, WB |
| Predicted Homology Based on Immunogen Sequence |
Cow: 79%; Dog: 86%; Guinea Pig: 79%; Horse: 86%; Human: 100%; Mouse: 100%; Pig: 93%; Rabbit: 100%; Rat: 100%; Sheep: 79%; Zebrafish: 79% |
| Image 1 | Human HeLa
 | WB Suggested Anti-MMP3 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:62500
Positive Control: Hela cell lysate |
|
| Image 2 | Human
 | Researcher: Department of Pathology, Hospital de Carabineros de Chile, Santiago, Chile
Application: IHC
Species+tissue/cell type: Control-Human small intestine, Sample-human colorectal cancer
Primary antibody dilution: 1:100
Secondary antibody: Biotinylated pig anti-rabbit+streptavidin-HRP |
|
| Image 3 | Articular cartilage secretome
 | MMP3 antibody - middle region (ARP42041_P050) validated by WB using Articular cartilage secretome at 1:1000. |
|
| Image 4 | Equine Cartilage Explants
 | Sample Type: Equine Cartilage ExplantsPrimary Dilution: 1:1000Secondary: Abcam ab97200 (Dilution: 1:20,000) |
|
