CRMP1 Antibody - N-terminal region (ARP41933_P050)

• Product Number: ARP41933_P050
• Name: CRMP1 Antibody - N-terminal region (ARP41933_P050)
• Protein Size (# AA): 572 amino acids
• Molecular Weight: 62kDa
• NCBI Gene Id: 1400
• Host: Rabbit
• Clonality: Polyclonal
• Concentration: 0.5 mg/ml
• Gene Full Name: Collapsin response mediator protein 1
• Alias Symbols: DRP1, DRP-1, CRMP-1, DPYSL1, ULIP-3
• Peptide Sequence: Synthetic peptide located within the following region: SYQGKKSIPHITSDRLLIKGGRIINDDQSLYADVYLEDGLIKQIGENLIV
• Product Format: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Reference: Weidemann,W., FEBS Lett. 580 (28-29), 6649-6654 (2006)
• Description of Target: CRMP1 is a member of a family of cytosolic phosphoproteins expressed exclusively in the nervous system. The protein is thought to be a part of the semaphorin signal transduction pathway implicated in semaphorin-induced growth cone collapse during neural development.This gene encodes a member of a family of cytosolic phosphoproteins expressed exclusively in the nervous system. The encoded protein is thought to be a part of the semaphorin signal transduction pathway implicated in semaphorin-induced growth cone collapse during neural development. Alternative splicing results in multiple transcript variants. This gene encodes a member of a family of cytosolic phosphoproteins expressed exclusively in the nervous system. The encoded protein is thought to be a part of the semaphorin signal transduction pathway implicated in semaphorin-induced growth cone collapse during neural development. Alternative splicing results in multiple transcript variants.
• Protein Interactions: AP3M1; DPYSL3; CRMP1; EXOSC8; GOLGA2; DPYSL2; DNAJB4; SEC24C; CUL1; HSPA4; ATP6V1B2; CORO1B; PARVA; OTUD6B; JMJD6; SWAP70; TUBB; TUBA1A; Gne; VIM; HTT; UBC; VCP; UBE2A; TK1; SRC; RGS2; DUSP4; BID; ANXA7; AMFR; YAE1D1; ZAK; DNAJB11; MAPK8IP2; SPRY2; RPS6KA
• Reconstitution and Storage: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
• Blocking Peptide: For anti-CRMP1 (ARP41933_P050) antibody is Catalog # AAP41933 (Previous Catalog # AAPP24470)
• Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human CRMP1
• Uniprot ID: Q14194
• Protein Name: Dihydropyrimidinase-related protein 1
• Protein Accession #: NP_001304
• Purification: Affinity Purified
• Nucleotide Accession #: NM_001313
• Tested Species Reactivity: Human, Mouse
• Gene Symbol: CRMP1
• Predicted Species Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish
• Application: IHC, WB, IP
• Predicted Homology Based on Immunogen Sequence: Cow: 93%; Dog: 93%; Guinea Pig: 93%; Horse: 93%; Human: 100%; Mouse: 92%; Rabbit: 86%; Rat: 93%; Zebrafish: 86%
• Image 1: Human 721_B
  
  WB Suggested Anti-CRMP1 Antibody Titration: 0.2-1 ug/ml
  ELISA Titer: 1:312500
  Positive Control: 721_B cell lysate
• Image 2: Mouse, Rat
  
  Sample Type: 2. mouse brain extracts (80ug)
  3. rat brain extract (80ug)
  Primary Antibody Dilution: 2ug/ml
  Secondary Antibody: IRDye 800CW goat anti-rabbit from Li-COR Bioscience
  Secondary Antibody Dilution: 1: 20,000
  Image Submitted by: Yuzhi Chen
  University of Arkansas for Medical Science 
• Image 3: Human NT2
  
  Sample Type: NT2 cells
  Red: Antibody
  Blue: DAPI
  Primary Dilution: 1ug/50ul antibody
  Secondary Antibody: Alexa goat anti-rabbit 594
  Image Submitted by: Yuzhi Chen, University of Arkansas for Medical Sciences  
• Image 4: Human Testis
  
  Rabbit Anti-CRMP1 antibody
  Catalog Number: ARP41933
  Formalin Fixed Paraffin Embedded Tissue: Human Testis
  Primary antibody Concentration: 1:100
  Secondary Antibody: Donkey anti-Rabbit-Cy3
  Secondary Antibody Concentration: 1:200
  Magnification: 20x
  Exposure Time: 0.5-2.0sec