KLK3 Antibody - middle region : Biotin (ARP41879_P050-Biotin)

Data Sheet
 
Product Number ARP41879_P050-Biotin
Product Page www.avivasysbio.com/klk3-antibody-middle-region-biotin-arp41879-p050-biotin.html
Name KLK3 Antibody - middle region : Biotin (ARP41879_P050-Biotin)
Protein Size (# AA) 261 amino acids
Molecular Weight 26kDa
Conjugation Biotin
NCBI Gene Id 354
Host Rabbit
Clonality Polyclonal
Concentration 0.5 mg/ml
Gene Full Name Kallikrein-related peptidase 3
Alias Symbols APS, PSA, hK3, KLK2A1
Peptide Sequence Synthetic peptide located within the following region: LRPGDDSSHDLMLLRLSEPAELTDAVKVMDLPTQEPALGTTCYASGWGSI
Product Format Liquid. Purified antibody supplied in 1x PBS buffer.
Description of Target Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its protein product is a protease present in seminal plasma. It is thought to function normally in the liquefaction of seminal coagulum, presumably by hydrolysis of the high molecular mass seminal vesicle protein. Serum level of this protein, called PSA in the clinical setting, is useful in the diagnosis and monitoring of prostatic carcinoma. Alternate splicing of this gene generates several transcript variants encoding different isoforms.
Protein Interactions ALB; PZP; SERPINA5; SERPINA1; SEMG2; SEMG1; PLG; PTHLH; IGFBP3; FN1; EPOR; SLPI; SERPINA3; A2M; POLR2A; AR; KAT5; RUVBL1; CTNNB1;
Reconstitution and Storage All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil). Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Datasheets/Manuals Printable datasheet for anti-KLK3 (ARP41879_P050-Biotin) antibody
Blocking Peptide For anti-KLK3 (ARP41879_P050-Biotin) antibody is Catalog # AAP41879
Uniprot ID P07288
Protein Name Prostate-specific antigen
Protein Accession # NP_001639
Purification Affinity Purified
Nucleotide Accession # NM_001648
Gene Symbol KLK3
Predicted Species Reactivity Human, Mouse, Rat, Dog
Application WB
Predicted Homology Based on Immunogen Sequence Dog: 77%; Human: 100%; Mouse: 86%; Rat: 86%
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