Product Number |
ARP41879_P050-Biotin |
Product Page |
www.avivasysbio.com/klk3-antibody-middle-region-biotin-arp41879-p050-biotin.html |
Name |
KLK3 Antibody - middle region : Biotin (ARP41879_P050-Biotin) |
Protein Size (# AA) |
261 amino acids |
Molecular Weight |
26kDa |
Conjugation |
Biotin |
NCBI Gene Id |
354 |
Host |
Rabbit |
Clonality |
Polyclonal |
Concentration |
0.5 mg/ml |
Gene Full Name |
Kallikrein-related peptidase 3 |
Alias Symbols |
APS, PSA, hK3, KLK2A1 |
Peptide Sequence |
Synthetic peptide located within the following region: LRPGDDSSHDLMLLRLSEPAELTDAVKVMDLPTQEPALGTTCYASGWGSI |
Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer. |
Description of Target |
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its protein product is a protease present in seminal plasma. It is thought to function normally in the liquefaction of seminal coagulum, presumably by hydrolysis of the high molecular mass seminal vesicle protein. Serum level of this protein, called PSA in the clinical setting, is useful in the diagnosis and monitoring of prostatic carcinoma. Alternate splicing of this gene generates several transcript variants encoding different isoforms. |
Protein Interactions |
ALB; PZP; SERPINA5; SERPINA1; SEMG2; SEMG1; PLG; PTHLH; IGFBP3; FN1; EPOR; SLPI; SERPINA3; A2M; POLR2A; AR; KAT5; RUVBL1; CTNNB1; |
Reconstitution and Storage |
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil). Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding. |
Datasheets/Manuals |
Printable datasheet for anti-KLK3 (ARP41879_P050-Biotin) antibody |
Blocking Peptide |
For anti-KLK3 (ARP41879_P050-Biotin) antibody is Catalog # AAP41879 |
Uniprot ID |
P07288 |
Protein Name |
Prostate-specific antigen |
Protein Accession # |
NP_001639 |
Purification |
Affinity Purified |
Nucleotide Accession # |
NM_001648 |
Gene Symbol |
KLK3 |
Predicted Species Reactivity |
Human, Mouse, Rat, Dog |
Application |
WB |
Predicted Homology Based on Immunogen Sequence |
Dog: 77%; Human: 100%; Mouse: 86%; Rat: 86% |
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