Product Number |
ARP41445_P050 |
Product Page |
www.avivasysbio.com/muc1-antibody-c-terminal-region-arp41445-p050.html |
Name |
MUC1 Antibody - C-terminal region (ARP41445_P050) |
Protein Size (# AA) |
203 amino acids |
Molecular Weight |
22kDa |
NCBI Gene Id |
4582 |
Host |
Rabbit |
Clonality |
Polyclonal |
Concentration |
0.5 mg/ml |
Gene Full Name |
Mucin 1, cell surface associated |
Alias Symbols |
EMA, MCD, PEM, PUM, KL-6, MAM6, MCKD, PEMT, CD227, H23AG, MCKD1, MUC-1, ADMCKD, ADTKD2, ADMCKD1, CA 15-3, MUC-1/X, MUC1/ZD, MUC-1/SEC |
Peptide Sequence |
Synthetic peptide located within the following region: GQLDIFPARDTYHPMSEYPTYHTHGRYVPPSSTDRSPYEKVSAGNGGSSL |
Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Description of Target |
MUC1 is a membrane bound, glycosylated phosphoprotein. The protein is anchored to the apical surface of many epithelia by a transmembrane domain, with the degree of glycosylation varying with cell type. It also includes a 20 aa variable number tandem repeat (VNTR) domain, with the number of repeats varying from 20 to 120 in different individuals. The protein serves a protective function by binding to pathogens and also functions in a cell signaling capacity. Overexpression, aberrant intracellular localization, and changes in glycosylation of this protein have been associated with carcinomas. |
Protein Interactions |
UBC; PPARG; IPO5; NUP62; EGFR; ABL1; SRC; JUN; TP53; TBP; IKBKG; TNFRSF1A; IKBKB; GRB2; ESR1; GALNT15; GALNT12; GALNT10; OSGEP; GSK3B; GALNT2; GALNT1; CTNND1; SIGLEC1; ERBB4; ERBB3; SOS1; PRKCD; ZAP70; APC; JUP; LYN; ERBB2; LCK; CTNNB1; GALNT4; BAX; CDKN1 |
Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
Datasheets/Manuals |
Printable datasheet for anti-MUC1 (ARP41445_P050) antibody |
Blocking Peptide |
For anti-MUC1 (ARP41445_P050) antibody is Catalog # AAP41445 (Previous Catalog # AAPP24182) |
Immunogen |
The immunogen is a synthetic peptide directed towards the C terminal region of human MUC1 |
Uniprot ID |
Q7Z552 |
Protein Name |
Mucin-1 |
Protein Accession # |
NP_001037855 |
Purification |
Affinity Purified |
Nucleotide Accession # |
NM_001044390 |
Tested Species Reactivity |
Human, Mouse, Pig |
Gene Symbol |
MUC1 |
Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Pig |
Application |
IHC, WB |
Predicted Homology Based on Immunogen Sequence |
Cow: 92%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100% |
Image 1 | Human stomach
| Sample Type: Human stomachPrimary Antibody Dilution: 1:1000Secondary Antibody: Anti-rabbit-HRPSecondary Antibody Dilution: 1:5000Color/Signal Descriptions: Brown: MUC1 Blue: NucleusGene Name: MUC1Submitted by: Dr. Sara Linden, University of Gothenburg |
|
Image 2 | Pig stomach
| Sample Type: Pig stomachPrimary Antibody Dilution: 1:5000 + 1:2000Secondary Antibody: Anti-rabbit-HRPSecondary Antibody Dilution: 1:1000Color/Signal Descriptions: Brown: MUC1 Blue: NucleusGene Name: MUC1Submitted by: Dr. Sara Linden, University of Gothenburg |
|
Image 3 | Pig stomach
| Sample Type: Pig stomachPrimary Antibody Dilution: 1:5000 + 1:2000Secondary Antibody: Anti-rabbit-HRPSecondary Antibody Dilution: 1:1000Color/Signal Descriptions: Brown: MUC1 Blue: NucleusGene Name: MUC1Submitted by: Dr. Sara Linden, University of Gothenburg |
|
Image 4 | Human Kidney
| Rabbit Anti-MUC1 Antibody Catalog Number: ARP41445 Paraffin Embedded Tissue: Human Kidney Cellular Data: Epithelial cells of renal tubule Antibody Concentration: 4.0-8.0 ug/ml Magnification: 400X |
|
Image 5 | Mouse
| NMuFG cells in ImmunohistochemistryDilutions 1:50 for the three primary antibodies and 1:100 for FITC-conjugated secondary. |
|
Image 6 | HepG2
| Host: Rabbit Target Name: MUC1 Sample Type: HepG2 Lane A: Primary Antibody Lane B: Primary Antibody + Blocking Peptide Primary Antibody Concentration: 1ug/ml Peptide Concentration: 5ug/ml Lysate Quantity: 25ug/lane/lane Gel Concentration: 0.12 |
|
Image 7 | Human HepG2
| Host: Rabbit Target Name: MUC1 Sample Type: HepG2 Whole cell lysates Antibody Dilution: 1.0ug/ml |
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