MUC1 Antibody - C-terminal region (ARP41445_P050)

Data Sheet
 
Product Number ARP41445_P050
Product Page www.avivasysbio.com/muc1-antibody-c-terminal-region-arp41445-p050.html
Name MUC1 Antibody - C-terminal region (ARP41445_P050)
Protein Size (# AA) 203 amino acids
Molecular Weight 22kDa
NCBI Gene Id 4582
Host Rabbit
Clonality Polyclonal
Concentration 0.5 mg/ml
Gene Full Name Mucin 1, cell surface associated
Alias Symbols EMA, MCD, PEM, PUM, KL-6, MAM6, MCKD, PEMT, CD227, H23AG, MCKD1, MUC-1, ADMCKD, ADTKD2, ADMCKD1, CA 15-3, MUC-1/X, MUC1/ZD, MUC-1/SEC
Peptide Sequence Synthetic peptide located within the following region: GQLDIFPARDTYHPMSEYPTYHTHGRYVPPSSTDRSPYEKVSAGNGGSSL
Product Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Description of Target MUC1 is a membrane bound, glycosylated phosphoprotein. The protein is anchored to the apical surface of many epithelia by a transmembrane domain, with the degree of glycosylation varying with cell type. It also includes a 20 aa variable number tandem repeat (VNTR) domain, with the number of repeats varying from 20 to 120 in different individuals. The protein serves a protective function by binding to pathogens and also functions in a cell signaling capacity. Overexpression, aberrant intracellular localization, and changes in glycosylation of this protein have been associated with carcinomas.
Protein Interactions UBC; PPARG; IPO5; NUP62; EGFR; ABL1; SRC; JUN; TP53; TBP; IKBKG; TNFRSF1A; IKBKB; GRB2; ESR1; GALNT15; GALNT12; GALNT10; OSGEP; GSK3B; GALNT2; GALNT1; CTNND1; SIGLEC1; ERBB4; ERBB3; SOS1; PRKCD; ZAP70; APC; JUP; LYN; ERBB2; LCK; CTNNB1; GALNT4; BAX; CDKN1
Reconstitution and Storage For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Datasheets/Manuals Printable datasheet for anti-MUC1 (ARP41445_P050) antibody
Blocking Peptide For anti-MUC1 (ARP41445_P050) antibody is Catalog # AAP41445 (Previous Catalog # AAPP24182)
Immunogen The immunogen is a synthetic peptide directed towards the C terminal region of human MUC1
Uniprot ID Q7Z552
Protein Name Mucin-1
Protein Accession # NP_001037855
Purification Affinity Purified
Nucleotide Accession # NM_001044390
Tested Species Reactivity Human, Mouse, Pig
Gene Symbol MUC1
Predicted Species Reactivity Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Pig
Application IHC, WB
Predicted Homology Based on Immunogen Sequence Cow: 92%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%
Image 1
Human stomach
Sample Type:
Human stomach
Primary Antibody Dilution:
1:1000
Secondary Antibody:
Anti-rabbit-HRP
Secondary Antibody Dilution:
1:5000
Color/Signal Descriptions:
Brown: MUC1 Blue: Nucleus
Gene Name:
MUC1
Submitted by:
Dr. Sara Linden, University of Gothenburg
Image 2
Pig stomach
Sample Type:
Pig stomach
Primary Antibody Dilution:
1:5000 + 1:2000
Secondary Antibody:
Anti-rabbit-HRP
Secondary Antibody Dilution:
1:1000
Color/Signal Descriptions:
Brown: MUC1 Blue: Nucleus
Gene Name:
MUC1
Submitted by:
Dr. Sara Linden, University of Gothenburg
Image 3
Pig stomach
Sample Type:
Pig stomach
Primary Antibody Dilution:
1:5000 + 1:2000
Secondary Antibody:
Anti-rabbit-HRP
Secondary Antibody Dilution:
1:1000
Color/Signal Descriptions:
Brown: MUC1 Blue: Nucleus
Gene Name:
MUC1
Submitted by:
Dr. Sara Linden, University of Gothenburg
Image 4
Human Kidney
Rabbit Anti-MUC1 Antibody
Catalog Number: ARP41445
Paraffin Embedded Tissue: Human Kidney
Cellular Data: Epithelial cells of renal tubule
Antibody Concentration: 4.0-8.0 ug/ml
Magnification: 400X
Image 5
Mouse
NMuFG cells in ImmunohistochemistryDilutions 1:50 for the three primary antibodies and 1:100 for FITC-conjugated secondary.
Image 6
HepG2
Host: Rabbit
Target Name: MUC1
Sample Type: HepG2
Lane A: Primary Antibody
Lane B: Primary Antibody + Blocking Peptide
Primary Antibody Concentration: 1ug/ml
Peptide Concentration: 5ug/ml
Lysate Quantity: 25ug/lane/lane
Gel Concentration: 0.12
Image 7
Human HepG2
Host: Rabbit
Target Name: MUC1
Sample Type: HepG2 Whole cell lysates
Antibody Dilution: 1.0ug/ml
 

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