| Product Number |
ARP41406_T100 |
| Product Page |
www.avivasysbio.com/fbp1-antibody-n-terminal-region-arp41406-t100.html |
| Name |
FBP1 Antibody - N-terminal region (ARP41406_T100) |
| Protein Size (# AA) |
338 amino acids |
| Molecular Weight |
37kDa |
| NCBI Gene Id |
2203 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
1.0 mg/ml |
| Gene Full Name |
Fructose-1,6-bisphosphatase 1 |
| Alias Symbols |
FBP |
| Peptide Sequence |
Synthetic peptide located within the following region: YVVCFDPLDGSSNIDCLVSVGTIFGIYRKKSTDEPSEKDALQPGRNLVAA |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reference |
Yanez,A.J., (2005) J. Cell. Physiol. 205 (1), 19-24 |
| Description of Target |
Fructose-1,6-bisphosphatase 1, a gluconeogenesis regulatory enzyme, catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate and inorganic phosphate. Fructose-1,6-diphosphatase deficiency is associated with hypoglycemia and metabolic acidosis.Fructose-1,6-bisphosphatase 1, a gluconeogenesis regulatory enzyme, catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate and inorganic phosphate. Fructose-1,6-diphosphatase deficiency is associated with hypoglycemia and metabolic acidosis. |
| Protein Interactions |
FBP2; FBP1; BIN1; KLRC2; ASL; UBC; POT1; TERF1; PARK2; HDAC6; PTK2; DYNC1I1; CSNK1E; BCL2L1; LNX1; PCNXL4; ATP5J2; ASCC2; RNF183; HSPA8; FXR2; ACTN1; |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-FBP1 (ARP41406_T100) antibody |
| Additional Information |
IHC Information: Jurkat cell lysate. Antibody concentration: 1.25 ug/ml. Gel concentration: 12%. |
| Blocking Peptide |
For anti-FBP1 (ARP41406_T100) antibody is Catalog # AAP41406 (Previous Catalog # AAPP24144) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the N terminal region of human FBP1 |
| Uniprot ID |
P09467 |
| Protein Name |
Fructose-1,6-bisphosphatase 1 |
| Publications |
Hu, Z. et al. Quantitative liver-specific protein fingerprint in blood: a signature for hepatotoxicity. Theranostics 4, 215-28 (2014). 24465277 |
| Protein Accession # |
NP_000498 |
| Purification |
Protein A purified |
| Nucleotide Accession # |
NM_000507 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
FBP1 |
| Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish |
| Application |
IHC, WB |
| Predicted Homology Based on Immunogen Sequence |
Cow: 86%; Dog: 86%; Guinea Pig: 93%; Horse: 93%; Human: 100%; Mouse: 100%; Rabbit: 93%; Rat: 86%; Zebrafish: 80% |
| Image 1 | Human Kidney
 | Rabbit Anti-FBP1 Antibody
Catalog Number: ARP41406
Paraffin Embedded Tissue: Human Kidney
Cellular Data: Epithelial cells of renal tubule
Antibody Concentration: 4.0-8.0 ug/ml
Magnification: 400X |
|
| Image 2 | Human Lung
 | Rabbit Anti-FBP1 Antibody
Catalog Number: ARP41406
Paraffin Embedded Tissue: Human alveolar cell
Cellular Data: Epithelial cells of renal tubule
Antibody Concentration: 4.0-8.0 ug/ml
Magnification: 400X |
|
| Image 3 |
 | 25 ug of the indicated Human whole cell extracts was loaded onto a 12% SDS-PAGE gel. 1 ug/mL of the antibody was used in this experiment. The protein may be modified by phosphoryation.
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