Product Number |
ARP41366_T100 |
Product Page |
www.avivasysbio.com/ass-antibody-n-terminal-region-arp41366-t100.html |
Name |
ASS Antibody - N-terminal region (ARP41366_T100) |
Protein Size (# AA) |
412 amino acids |
Molecular Weight |
45kDa |
NCBI Gene Id |
445 |
Host |
Rabbit |
Clonality |
Polyclonal |
Concentration |
1.0 mg/ml |
Gene Full Name |
Argininosuccinate synthase 1 |
Description |
|
Alias Symbols |
ASS, CTLN1 |
Peptide Sequence |
Synthetic peptide located within the following region: YSGGLDTSCILVWLKEQGYDVIAYLANIGQKEDFEEARKKALKLGAKKVF |
Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reference |
Hao,G., (2004) J. Biol. Chem. 279 (35), 36192-36200 |
Description of Target |
ASS catalyzes the penultimate step of the arginine biosynthetic pathway.The protein encoded by this gene catalyzes the penultimate step of the arginine biosynthetic pathway. There are approximately 10 to 14 copies of this gene including the pseudogenes scattered across the human genome, among which the one located on chromosome 9 appears to be the only functional gene for argininosuccinate synthetase. Mutations in the chromosome 9 copy of ASS cause citrullinemia. Two transcript variants encoding the same protein have been found for this gene. |
Protein Interactions |
ASS1; UBC; ASB18; ASB9; NHLRC2; ATG3; CNDP2; NANS; TNFAIP8; NAMPT; DPP3; RPL23; CTSA; PEPD; MVD; HSPA9; GSS; GBP2; EIF4E; DLD; CAPN1; FBXO6; LATS1; MT2A; MLH1; JAK2; PTPN1; GIT2; SPR; APP; USP4; TERF2; TERF1; SUMO2; AI837181; MYC; ASCC2; AKTIP; ARAF; ELN; |
Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
Datasheets/Manuals |
Printable datasheet for anti-ASS1 (ARP41366_T100) antibody |
Blocking Peptide |
For anti-ASS1 (ARP41366_T100) antibody is Catalog # AAP41366 (Previous Catalog # AAPP24105) |
Immunogen |
The immunogen is a synthetic peptide directed towards the N terminal region of human ASS |
Uniprot ID |
P00966 |
Protein Name |
Argininosuccinate synthase |
Publications |
Aberrant expression and distribution of enzymes of the urea cycle and other ammonia metabolizing pathways in dogs with congenital portosystemic shunts. PLoS One. 9, e100077 (2014). 24945279
Argininosuccinate neurotoxicity and prevention by creatine in argininosuccinate lyase deficiency: An in vitro study in rat three-dimensional organotypic brain cell cultures. J Inherit Metab Dis. 42, 1077-1087 (2019) 30907007 |
Protein Accession # |
NP_446464 |
Purification |
Protein A purified |
Nucleotide Accession # |
NM_054012 |
Tested Species Reactivity |
Human |
Gene Symbol |
ASS1 |
Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Goat, Guinea Pig, Horse, Yeast, Zebrafish |
Application |
IHC, WB |
Predicted Homology Based on Immunogen Sequence |
Cow: 100%; Dog: 100%; Goat: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rat: 100%; Yeast: 86%; Zebrafish: 79% |
Image 1 | Human Kidney
| Rabbit Anti-ASS Antibody Catalog Number: ARP41366 Paraffin Embedded Tissue: Human Kidney Cellular Data: Epithelial cells of renal tubule Antibody Concentration: 4.0-8.0 ug/ml Magnification: 400X |
|
Image 2 | Human HepG2
| WB Suggested Anti-ASS Antibody Titration: 2.5ug/ml Positive Control: HepG2 cell lysate |
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