WDR4 Antibody - C-terminal region (ARP41321_T100)

Data Sheet
 
Product Number ARP41321_T100
Product Page www.avivasysbio.com/wdr4-antibody-c-terminal-region-arp41321-t100.html
Name WDR4 Antibody - C-terminal region (ARP41321_T100)
Protein Size (# AA) 412 amino acids
Molecular Weight 45kDa
Subunit WDR4
NCBI Gene Id 10785
Host Rabbit
Clonality Polyclonal
Concentration 1.0 mg/ml
Gene Full Name WD repeat domain 4
Alias Symbols hWH, Wuho, MIGSB, TRM82, GAMOS6, TRMT82
Peptide Sequence Synthetic peptide located within the following region: AGADASFSSLYKATFDNVTSYLKKKEERLQQQLEKKQRRRSPPPGPDGHA
Product Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reference Michaud,J., (2000) Genomics 68 (1), 71-79
Description of Target WDR4 is a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This gene is excluded as a candidate for a form of nonsyndromic deafness (DFNB10), but is still a candidate for other disorders mapped to 21q22.3 as well as for the development of Down syndrome phenotypes.This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This gene is excluded as a candidate for a form of nonsyndromic deafness (DFNB10), but is still a candidate for other disorders mapped to 21q22.3 as well as for the development of Down syndrome phenotypes. Two transcript variants encoding the same protein have been found for this gene.
Protein Interactions FAM118A; RABGGTB; METTL1; LGR4; CUL5; PDE12; WDR92; DCTPP1; P3H1; ELAC2; XPO5; NPLOC4; UBE2R2; DPP8; PPME1; ERO1L; UBQLN2; DBNL; KIAA1279; ARIH1; HSPBP1; PLIN3; ACTR2; SAE1; ASMTL; OGT; SURF2; SRP14; DNAJB1; DDX5; ALAD; ADSL; ERC1; UBP1; UBE2D1; TERF2; TE
Reconstitution and Storage For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Datasheets/Manuals Printable datasheet for anti-WDR4 (ARP41321_T100) antibody
Blocking Peptide For anti-WDR4 (ARP41321_T100) antibody is Catalog # AAP41321 (Previous Catalog # AAPP22676)
Immunogen The immunogen is a synthetic peptide directed towards the C terminal region of human WDR4
Uniprot ID P57081
Protein Name tRNA (guanine-N(7)-)-methyltransferase subunit WDR4
Protein Accession # NP_387510
Purification Protein A purified
Nucleotide Accession # NM_033661
Tested Species Reactivity Human
Gene Symbol WDR4
Predicted Species Reactivity Human, Mouse, Rat, Cow, Horse, Pig, Rabbit, Yeast
Application IHC, WB
Predicted Homology Based on Immunogen Sequence Cow: 93%; Horse: 93%; Human: 100%; Mouse: 87%; Pig: 90%; Rabbit: 83%; Rat: 75%; Yeast: 75%
Image 1
Human HepG2
WB Suggested Anti-WDR4 Antibody Titration: 1.25ug/ml
Positive Control: HepG2 cell lysate
Image 2
Human Kidney
Rabbit Anti-WDR4 Antibody
Catalog Number: ARP41321
Paraffin Embedded Tissue: Human Kidney
Cellular Data: Epithelial cells of renal tubule
Antibody Concentration: 4.0-8.0 ug/ml
Magnification: 400X
 

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