Product Number |
ARP41321_T100 |
Product Page |
www.avivasysbio.com/wdr4-antibody-c-terminal-region-arp41321-t100.html |
Name |
WDR4 Antibody - C-terminal region (ARP41321_T100) |
Protein Size (# AA) |
412 amino acids |
Molecular Weight |
45kDa |
Subunit |
WDR4 |
NCBI Gene Id |
10785 |
Host |
Rabbit |
Clonality |
Polyclonal |
Concentration |
1.0 mg/ml |
Gene Full Name |
WD repeat domain 4 |
Alias Symbols |
hWH, Wuho, MIGSB, TRM82, GAMOS6, TRMT82 |
Peptide Sequence |
Synthetic peptide located within the following region: AGADASFSSLYKATFDNVTSYLKKKEERLQQQLEKKQRRRSPPPGPDGHA |
Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reference |
Michaud,J., (2000) Genomics 68 (1), 71-79 |
Description of Target |
WDR4 is a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This gene is excluded as a candidate for a form of nonsyndromic deafness (DFNB10), but is still a candidate for other disorders mapped to 21q22.3 as well as for the development of Down syndrome phenotypes.This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This gene is excluded as a candidate for a form of nonsyndromic deafness (DFNB10), but is still a candidate for other disorders mapped to 21q22.3 as well as for the development of Down syndrome phenotypes. Two transcript variants encoding the same protein have been found for this gene. |
Protein Interactions |
FAM118A; RABGGTB; METTL1; LGR4; CUL5; PDE12; WDR92; DCTPP1; P3H1; ELAC2; XPO5; NPLOC4; UBE2R2; DPP8; PPME1; ERO1L; UBQLN2; DBNL; KIAA1279; ARIH1; HSPBP1; PLIN3; ACTR2; SAE1; ASMTL; OGT; SURF2; SRP14; DNAJB1; DDX5; ALAD; ADSL; ERC1; UBP1; UBE2D1; TERF2; TE |
Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
Datasheets/Manuals |
Printable datasheet for anti-WDR4 (ARP41321_T100) antibody |
Blocking Peptide |
For anti-WDR4 (ARP41321_T100) antibody is Catalog # AAP41321 (Previous Catalog # AAPP22676) |
Immunogen |
The immunogen is a synthetic peptide directed towards the C terminal region of human WDR4 |
Uniprot ID |
P57081 |
Protein Name |
tRNA (guanine-N(7)-)-methyltransferase subunit WDR4 |
Protein Accession # |
NP_387510 |
Purification |
Protein A purified |
Nucleotide Accession # |
NM_033661 |
Tested Species Reactivity |
Human |
Gene Symbol |
WDR4 |
Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Horse, Pig, Rabbit, Yeast |
Application |
IHC, WB |
Predicted Homology Based on Immunogen Sequence |
Cow: 93%; Horse: 93%; Human: 100%; Mouse: 87%; Pig: 90%; Rabbit: 83%; Rat: 75%; Yeast: 75% |
Image 1 | Human HepG2
| WB Suggested Anti-WDR4 Antibody Titration: 1.25ug/ml Positive Control: HepG2 cell lysate |
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Image 2 | Human Kidney
| Rabbit Anti-WDR4 Antibody Catalog Number: ARP41321 Paraffin Embedded Tissue: Human Kidney Cellular Data: Epithelial cells of renal tubule Antibody Concentration: 4.0-8.0 ug/ml Magnification: 400X |
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