MBNL1 Antibody - middle region (ARP41227_P050)

Data Sheet
 
Product Number ARP41227_P050
Product Page www.avivasysbio.com/mbnl1-antibody-middle-region-arp41227-p050.html
Name MBNL1 Antibody - middle region (ARP41227_P050)
Protein Size (# AA) 388 amino acids
Molecular Weight 42 kDa
NCBI Gene Id 4154
Host Rabbit
Clonality Polyclonal
Concentration 0.5 mg/ml
Gene Full Name Muscleblind-like splicing regulator 1
Alias Symbols EXP, MBNL
Peptide Sequence Synthetic peptide located within the following region: AMTQSAVKSLKRPLEATFDLGIPQAVLPPLPKRPALEKTNGATAVFNTGI
Product Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reference Strausberg,R., (2003) Direct Submission
Description of Target MBNL1 contains 4 C3H1-type zinc fingers and binds to CUG triplet repeat expansion dsRNA.
Protein Interactions DAB1; AES; AEN; UBC; ABI3BP; ZNHIT3; VCAM1; ITGA4; IDH3A; FN1; TIAL1; APP; BIN1; ITSN2; DDX17; HNRNPL; HNRNPK; HNRNPH3; HNRNPH2; HNRNPH1; HNRNPF; HNRNPA2B1; DHX9; DDX5;
Reconstitution and Storage For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Enhanced Validation
Relative Expression (Western Blot) Avivasheild
Datasheets/Manuals Printable datasheet for anti-MBNL1 (ARP41227_P050) antibody
Blocking Peptide For anti-MBNL1 (ARP41227_P050) antibody is Catalog # AAP41227 (Previous Catalog # AAPS01306)
Immunogen The immunogen is a synthetic peptide directed towards the middle region of human MBNL1
Uniprot ID Q86VM6
Protein Name MBNL1 protein EMBL AAH50535.1
Publications

Muscleblind-like 1 is required for normal heart valve development in vivo. BMC Dev. Biol. 15, 36 (2015). 26472242

Sample Type Confirmation

MBNL1 is strongly supported by BioGPS gene expression data to be expressed in Jurkat

Protein Accession # AAH50535
Purification Affinity Purified
Nucleotide Accession # NM_021038
Tested Species Reactivity Human
Gene Symbol MBNL1
Predicted Species Reactivity Human, Mouse, Rat, Dog, Horse, Pig, Rabbit, Zebrafish
Application IHC, WB
Predicted Homology Based on Immunogen Sequence Dog: 100%; Horse: 100%; Human: 100%; Mouse: 79%; Pig: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%
Image 1
Human Heart
Rabbit Anti-MBNL1 Antibody
Catalog Number: ARP41227
Paraffin Embedded Tissue: Human cardiac cell
Cellular Data: Epithelial cells of renal tubule
Antibody Concentration: 4.0-8.0 ug/ml
Magnification: 400X
Image 2
Human Heart
Rabbit Anti-MBNL1 Antibody
Catalog Number: ARP41227
Paraffin Embedded Tissue: Human Heart
Cellular Data: Myocardial cells
Antibody Concentration: 4.0-8.0 ug/ml
Magnification: 400X
Image 3

25 ug of the indicated Human whole cell extracts was loaded onto a 12% SDS-PAGE gel. 3 ug/mL of the antibody was used in this experiment. The peptide sequence is present in a 40 kDa isoform.
 

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