Product Number |
ARP41227_P050 |
Product Page |
www.avivasysbio.com/mbnl1-antibody-middle-region-arp41227-p050.html |
Name |
MBNL1 Antibody - middle region (ARP41227_P050) |
Protein Size (# AA) |
388 amino acids |
Molecular Weight |
42 kDa |
NCBI Gene Id |
4154 |
Host |
Rabbit |
Clonality |
Polyclonal |
Concentration |
0.5 mg/ml |
Gene Full Name |
Muscleblind-like splicing regulator 1 |
Alias Symbols |
EXP, MBNL |
Peptide Sequence |
Synthetic peptide located within the following region: AMTQSAVKSLKRPLEATFDLGIPQAVLPPLPKRPALEKTNGATAVFNTGI |
Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reference |
Strausberg,R., (2003) Direct Submission |
Description of Target |
MBNL1 contains 4 C3H1-type zinc fingers and binds to CUG triplet repeat expansion dsRNA. |
Protein Interactions |
DAB1; AES; AEN; UBC; ABI3BP; ZNHIT3; VCAM1; ITGA4; IDH3A; FN1; TIAL1; APP; BIN1; ITSN2; DDX17; HNRNPL; HNRNPK; HNRNPH3; HNRNPH2; HNRNPH1; HNRNPF; HNRNPA2B1; DHX9; DDX5; |
Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
Enhanced Validation |
Relative Expression (Western Blot) |
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Datasheets/Manuals |
Printable datasheet for anti-MBNL1 (ARP41227_P050) antibody |
Blocking Peptide |
For anti-MBNL1 (ARP41227_P050) antibody is Catalog # AAP41227 (Previous Catalog # AAPS01306) |
Immunogen |
The immunogen is a synthetic peptide directed towards the middle region of human MBNL1 |
Uniprot ID |
Q86VM6 |
Protein Name |
MBNL1 protein EMBL AAH50535.1 |
Publications |
Muscleblind-like 1 is required for normal heart valve development in vivo. BMC Dev. Biol. 15, 36 (2015). 26472242 |
Sample Type Confirmation |
MBNL1 is strongly supported by BioGPS gene expression data to be expressed in Jurkat |
Protein Accession # |
AAH50535 |
Purification |
Affinity Purified |
Nucleotide Accession # |
NM_021038 |
Tested Species Reactivity |
Human |
Gene Symbol |
MBNL1 |
Predicted Species Reactivity |
Human, Mouse, Rat, Dog, Horse, Pig, Rabbit, Zebrafish |
Application |
IHC, WB |
Predicted Homology Based on Immunogen Sequence |
Dog: 100%; Horse: 100%; Human: 100%; Mouse: 79%; Pig: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100% |
Image 1 | Human Heart
| Rabbit Anti-MBNL1 Antibody Catalog Number: ARP41227 Paraffin Embedded Tissue: Human cardiac cell Cellular Data: Epithelial cells of renal tubule Antibody Concentration: 4.0-8.0 ug/ml Magnification: 400X |
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Image 2 | Human Heart
| Rabbit Anti-MBNL1 Antibody Catalog Number: ARP41227 Paraffin Embedded Tissue: Human Heart Cellular Data: Myocardial cells Antibody Concentration: 4.0-8.0 ug/ml Magnification: 400X |
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Image 3 |
| 25 ug of the indicated Human whole cell extracts was loaded onto a 12% SDS-PAGE gel. 3 ug/mL of the antibody was used in this experiment. The peptide sequence is present in a 40 kDa isoform.
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