Product Number |
ARP40847_P050 |
Product Page |
www.avivasysbio.com/larp7-antibody-c-terminal-region-arp40847-p050.html |
Name |
LARP7 Antibody - C-terminal region (ARP40847_P050) |
Protein Size (# AA) |
582 amino acids |
Molecular Weight |
67kDa |
NCBI Gene Id |
51574 |
Host |
Rabbit |
Clonality |
Polyclonal |
Concentration |
0.5 mg/ml |
Gene Full Name |
La ribonucleoprotein domain family, member 7 |
Description |
|
Alias Symbols |
ALAZS, PIP7S, hLARP7, HDCMA18P |
Peptide Sequence |
Synthetic peptide located within the following region: WQKILVDRQAKLNQPREKKRGTEKLITKAEKIRLAKTQQASKHIRFSEYD |
Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reference |
Krueger,B.J., (2008) Nucleic Acids Res. 36 (7), 2219-2229 |
Description of Target |
The function remains unknown. |
Protein Interactions |
HEXIM1; AFF1; CDK9; CCNT1; UBC; LIN28B; LIN28A; MEPCE; RNF2; VCPIP1; RABEP2; BRCC3; RPP25; CD2AP; JMJD6; HNRNPR; TRIM28; HUWE1; MTA2; SPAG9; TSC22D1; HDAC1; NR3C1; RN7SK; RPS16; HNRNPA1; CSNK2A1; tat; PAXIP1; BARD1; APP; CAND1; SIRT7; PRPF40A; Ybx1; Nhp2l |
Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
Datasheets/Manuals |
Printable datasheet for anti-LARP7 (ARP40847_P050) antibody |
Blocking Peptide |
For anti-LARP7 (ARP40847_P050) antibody is Catalog # AAP40847 (Previous Catalog # AAPY01099) |
Immunogen |
The immunogen is a synthetic peptide directed towards the C terminal region of human LARP7 |
Uniprot ID |
Q4G0J3 |
Protein Name |
La-related protein 7 |
Publications |
Muniz, L., Egloff, S. & Kiss, T. RNA elements directing in vivo assembly of the 7SK/MePCE/Larp7 transcriptional regulatory snRNP. Nucleic Acids Res. 41, 4686-98 (2013). 23471002
The 7SK snRNP associates with the little elongation complex to promote snRNA gene expression. EMBO J. 36, 934-948 (2017). 28254838
The HIV-1 Tat protein recruits a ubiquitin ligase to reorganize the 7SK snRNP for transcriptional activation. Elife. 7, (2018). 29845934 |
Protein Accession # |
NP_056269 |
Purification |
Affinity Purified |
Nucleotide Accession # |
NM_015454 |
Tested Species Reactivity |
Human |
Gene Symbol |
LARP7 |
Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit |
Application |
WB |
Predicted Homology Based on Immunogen Sequence |
Cow: 93%; Dog: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 93%; Pig: 100%; Rabbit: 93%; Rat: 100% |
Image 1 | Human Hela
| Host: Rabbit Target Name: LARP7 Sample Tissue: Human Hela Antibody Dilution: 1.0ug/ml |
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