| Product Number |
ARP40475_P050 |
| Product Page |
www.avivasysbio.com/prkra-antibody-middle-region-arp40475-p050.html |
| Name |
PRKRA Antibody - middle region (ARP40475_P050) |
| Protein Size (# AA) |
313 amino acids |
| Molecular Weight |
34kDa |
| NCBI Gene Id |
8575 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
0.5 mg/ml |
| Gene Full Name |
Protein kinase, interferon-inducible double stranded RNA dependent activator |
| Alias Symbols |
RAX, PACT, DYT16, HSD14 |
| Peptide Sequence |
Synthetic peptide located within the following region: RLPEYTLSQEGGPAHKREYTTICRLESFMETGKGASKKQAKRNAAEKFLA |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reference |
Lee,Y., (2006) EMBO J. 25 (3), 522-532 |
| Description of Target |
PRKRA contains 3 DRBM (double-stranded RNA-binding) domains. It appears to have a pro-apoptotic function that may be suppressed in the presence of growth factor and activates EIF2AK2 in absence of double stranded RNA (dsRNA). |
| Protein Interactions |
ZMAT3; PRKRA; TARBP2; LYAR; STAU1; UBC; H1F0; EIF2AK2; CCDC124; C1orf35; DDX50; NOC3L; NOP16; STAU2; ZNF346; GTPBP4; DICER1; RBM34; EBNA1BP2; IFRD2; TCOF1; BMI1; SRPK3; POLR2G; MDC1; CAND1; UBE2I; SIRT7; ZFP28; KIAA1377; NKRF; SNX5; RABEPK; CEBPZ; SHC1; Z |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-PRKRA (ARP40475_P050) antibody |
| Blocking Peptide |
For anti-PRKRA (ARP40475_P050) antibody is Catalog # AAP40475 (Previous Catalog # AAPP22243) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the middle region of human PRKRA |
| Uniprot ID |
O75569 |
| Protein Name |
Interferon-inducible double stranded RNA-dependent protein kinase activator A |
| Publications |
Yoshida, K. et al. Interaction between PKR and PACT mediated by LPS-inducible NF-κB in human gingival cells. J. Cell. Biochem. 113, 165-73 (2012). 21882225 |
| Sample Type Confirmation |
PRKRA is supported by BioGPS gene expression data to be expressed in Jurkat |
| Protein Accession # |
NP_003681 |
| Purification |
Affinity Purified |
| Nucleotide Accession # |
NM_003690 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
PRKRA |
| Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit |
| Application |
IHC, WB |
| Predicted Homology Based on Immunogen Sequence |
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100% |
| Image 1 | Human Jurkat
 | WB Suggested Anti-PRKRA Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:62500
Positive Control: Jurkat cell lysatePRKRA is supported by BioGPS gene expression data to be expressed in Jurkat |
|
| Image 2 | Human Stomach
 | Rabbit Anti-PRKRA Antibody
Catalog Number: ARP40475
Paraffin Embedded Tissue: Human Stomach
Cellular Data: Epithelial cells of fundic gland
Antibody Concentration: 4.0-8.0 ug/ml
Magnification: 400X |
|
