| Product Number |
ARP40474_P050 |
| Product Page |
www.avivasysbio.com/khsrp-antibody-middle-region-arp40474-p050.html |
| Name |
KHSRP Antibody - middle region (ARP40474_P050) |
| Protein Size (# AA) |
711 amino acids |
| Molecular Weight |
73kDa |
| NCBI Gene Id |
8570 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
0.5 mg/ml |
| Gene Full Name |
KH-type splicing regulatory protein |
| Alias Symbols |
p75, FBP2, KSRP, FUBP2 |
| Peptide Sequence |
Synthetic peptide located within the following region: WEEYYKKQAQVATGGGPGAPPGSQPDYSAAWAEYYRQQAAYYGQTPGPGG |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Description of Target |
KHSRP binds to the dendritic targeting element and may play a role in mRNA trafficking. It is part of a ternary complex that binds to the downstream control sequence (DCS) of the pre-mRNA. KHSRP mediates exon inclusion in transcripts that are subject to tissue-specific alternative splicing. It may interact with single-stranded DNA from the far-upstream element (FUSE).It is also involved in degradation of inherently unstable mRNAs that contain AU-rich elements (AREs) in their 3'-UTR, possibly by recruiting degradation machinery to ARE-containing mRNAs. |
| Protein Interactions |
HUWE1; Bace1; UBC; STAU1; LGR4; MDM2; WWOX; SUZ12; EED; RNF2; NAP1L4; HNRNPD; GFPT1; GARS; APBB1; ALDH16A1; TARDBP; CD81; MPG; UBL4A; WHSC1; VCAM1; ITGA4; FN1; STRIP1; ASF1B; CPLX1; CIRBP; SUMO1; RAE1; CAND1; COPS5; CUL1; CUL2; CUL3; CUL4B; CUL5; NEDD8; C |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-KHSRP (ARP40474_P050) antibody |
| Blocking Peptide |
For anti-KHSRP (ARP40474_P050) antibody is Catalog # AAP40474 |
| Immunogen |
The immunogen is a synthetic peptide directed towards the middle region of Human KHSRP |
| Uniprot ID |
Q92945 |
| Protein Name |
Far upstream element-binding protein 2 |
| Publications |
Ahn, Y.-H. et al. Electrophilic tuning of the chemoprotective natural product sulforaphane. Proc. Natl. Acad. Sci. U. S. A. 107, 9590-5 (2010). 20439747 |
| Sample Type Confirmation |
KHSRP is strongly supported by BioGPS gene expression data to be expressed in HEK293T |
| Protein Accession # |
NP_003676 |
| Purification |
Affinity Purified |
| Nucleotide Accession # |
NM_003685 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
KHSRP |
| Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish |
| Application |
IHC, WB |
| Predicted Homology Based on Immunogen Sequence |
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 93%; Rat: 100%; Zebrafish: 100% |
| Image 1 | Human HEK293T
 | WB Suggested Anti-KHSRP Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:1562500
Positive Control: 293T cell lysateKHSRP is strongly supported by BioGPS gene expression data to be expressed in Human HEK293T cells |
|
| Image 2 | Human Heart
 | Rabbit Anti-KHSRP Antibody
Catalog Number: ARP40474
Paraffin Embedded Tissue: Human Heart cell Cellular Data: cardiac cell of renal tubule
Antibody Concentration: 4.0-8.0 ug/ml
Magnification: 400X |
|
