| Product Number |
ARP40466_P050 |
| Product Page |
www.avivasysbio.com/xpo1-antibody-middle-region-arp40466-p050.html |
| Name |
XPO1 Antibody - middle region (ARP40466_P050) |
| Protein Size (# AA) |
1071 amino acids |
| Molecular Weight |
123kDa |
| NCBI Gene Id |
7514 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
0.5 mg/ml |
| Gene Full Name |
Exportin 1 (CRM1 homolog, yeast) |
| Alias Symbols |
emb, CRM1, exp1, CRM-1 |
| Peptide Sequence |
Synthetic peptide located within the following region: IPAFKEHLRDFLVQIKEFAGEDTSDLFLEEREIALRQADEEKHKRQMSVP |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reference |
Cheong,J.K., (2008) J. Biol. Chem. 283 (17), 11661-11676 |
| Description of Target |
XPO1 mediates leucine-rich nuclear export signal (NES)-dependent protein transport. Exportin 1 specifically inhibits the nuclear export of Rev and U snRNAs. It is also involved in the control of several cellular processes by controlling the localization of cyclin B, MPAK, and MAPKAP kinase 2. This protein also regulates NFAT and AP-1.The protein encoded by this gene mediates leucine-rich nuclear export signal (NES)-dependent protein transport. Exportin 1 specifically inhibits the nuclear export of Rev and U snRNAs. It is involved in the control of several cellular processes by controlling the localization of cyclin B, MPAK, and MAPKAP kinase 2. This protein also regulates NFAT and AP-1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. |
| Protein Interactions |
ABL1; UBC; HUWE1; ELAVL1; KEAP1; SUMO2; SUMO3; USP16; STAU1; CDC37L1; RNF2; rev; TUBB; SCPEP1; CAMK1D; DCPS; HSPA1L; HNRNPK; GNAI3; EEF2; CAPN2; TWF2; FERMT2; UBA3; NAE1; STK24; YWHAH; YWHAE; VCL; TUFM; PCYT2; PPP5C; PPP1CA; EGFR; LOC366310; CLN5; CLN3; S |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-XPO1 (ARP40466_P050) antibody |
| Blocking Peptide |
For anti-XPO1 (ARP40466_P050) antibody is Catalog # AAP40466 (Previous Catalog # AAPP22234) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the middle region of human XPO1 |
| Uniprot ID |
O14980 |
| Protein Name |
Exportin-1 |
| Sample Type Confirmation |
XPO1 is supported by BioGPS gene expression data to be expressed in HEK293T |
| Protein Accession # |
NP_003391 |
| Purification |
Affinity Purified |
| Nucleotide Accession # |
NM_003400 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
XPO1 |
| Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit, Zebrafish |
| Application |
IHC, WB |
| Predicted Homology Based on Immunogen Sequence |
Cow: 86%; Dog: 86%; Guinea Pig: 77%; Horse: 86%; Human: 100%; Mouse: 86%; Pig: 86%; Rabbit: 86%; Rat: 86%; Zebrafish: 79% |
| Image 1 | Human Heart
 | Rabbit Anti-XPO1 antibody
Catalog Number: ARP40466
Paraffin Embedded Tissue: Human Heart cell Cellular Data: cardiac cell of renal tubule
Antibody Concentration: 4.0-8.0 ug/ml
Magnification: 400X |
|
| Image 2 | Human 293T
 | WB Suggested Anti-XPO1 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:312500
Positive Control: 293T cell lysateXPO1 is supported by BioGPS gene expression data to be expressed in HEK293T |
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