| Product Number |
ARP40285_P050 |
| Product Page |
www.avivasysbio.com/u2af2-antibody-c-terminal-region-arp40285-p050.html |
| Name |
U2AF2 Antibody - C-terminal region (ARP40285_P050) |
| Protein Size (# AA) |
471 amino acids |
| Molecular Weight |
53kDa |
| NCBI Gene Id |
11338 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
0.5 mg/ml |
| Gene Full Name |
U2 small nuclear RNA auxiliary factor 2 |
| Alias Symbols |
U2AF65 |
| Peptide Sequence |
Synthetic peptide located within the following region: TEVLCLMNMVLPEELLDDEEYEEIVEDVRDECSKYGLVKSIEIPRPVDGV |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Description of Target |
U2 auxiliary factor (U2AF), comprised of a large and a small subunit, is a non-snRNP protein required for the binding of U2 snRNP to the pre-mRNA branch site. U2AF2 is the U2AF large subunit which contains a sequence-specific RNA-binding region with 3 RNA recognition motifs and an Arg/Ser-rich domain necessary for splicing. The large subunit binds to the polypyrimidine tract of introns early during spliceosome assembly. |
| Protein Interactions |
THAP1; PUF60; U2AF1; SNRPA; AES; DACH1; SUMO3; UBC; SUZ12; EED; TERF1; EZH2; RNF2; PRPF40A; TCERG1; APBB1; PIN1; SH3RF2; SRPK2; SRPK1; SF1; SRSF1; RBM39; QKI; SCAF11; PRPF3; RBM10; RBM4; SMAD5; IL7R; HNRNPK; HNRNPD; HLA-DMA; SUGP1; CCAR1; SAP30BP; RBFOX2; |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-U2AF2 (ARP40285_P050) antibody |
| Blocking Peptide |
For anti-U2AF2 (ARP40285_P050) antibody is Catalog # AAP40285 |
| Immunogen |
The immunogen is a synthetic peptide directed towards the C terminal region of human U2AF2 |
| Uniprot ID |
Q80XR5 |
| Protein Name |
U2 small nuclear ribonucleoprotein auxiliary factor (U2AF) 2, isoform CRA_a EMBL EDL31286.1 |
| Sample Type Confirmation |
There is BioGPS gene expression data showing that U2AF2 is expressed in HepG2 |
| Protein Accession # |
NP_001012496 |
| Purification |
Affinity Purified |
| Nucleotide Accession # |
NM_001012478 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
U2AF2 |
| Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Yeast, Zebrafish |
| Application |
WB |
| Predicted Homology Based on Immunogen Sequence |
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rat: 100%; Yeast: 79%; Zebrafish: 100% |
| Image 1 | HepG2
 | WB Suggested Anti-U2AF2 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:62500
Positive Control: HepG2 cell lysateThere is BioGPS gene expression data showing that U2AF2 is expressed in HepG2 |
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