| Product Number |
ARP40183_P050 |
| Product Page |
www.avivasysbio.com/prmt3-antibody-middle-region-arp40183-p050.html |
| Name |
PRMT3 Antibody - middle region (ARP40183_P050) |
| Protein Size (# AA) |
531 amino acids |
| Molecular Weight |
60kDa |
| NCBI Gene Id |
10196 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
0.5 mg/ml |
| Gene Full Name |
Protein arginine methyltransferase 3 |
| Alias Symbols |
HRMT1L3 |
| Peptide Sequence |
Synthetic peptide located within the following region: LEFSSDFTLKITRTSMCTAIAGYFDIYFEKNCHNRVVFSTGPQSTKTHWK |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reference |
Singh,V., (2004) Oncogene 23 (47), 7761-7771 |
| Description of Target |
Type I protein arginine N-methyltransferases (PRMTs), such as PRMT3, catalyze the formation of asymmetric N(G),N(G)-dimethylarginine (ADMA) residues in proteins.Type I protein arginine N-methyltransferases (PRMTs), such as PRMT3, catalyze the formation of asymmetric N(G),N(G)-dimethylarginine (ADMA) residues in proteins (Tang et al., 1998 [PubMed 9642256]).[supplied by OMIM]. Sequence Note: removed 2 bases from the 5' end that did not align to the reference genome assembly. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-2630 BC064831.1 3-2632 |
| Protein Interactions |
ARFIP1; SAMHD1; XPO7; FAF1; HSPH1; SEC23A; YAP1; RASSF2; HIRIP3; HIST1H4A; USP11; XRCC5; TROVE2; PPARD; PLOD2; OSBP; NARS; LIG1; IDE; GFPT1; EIF4B; CTNNA1; HNRNPA1; VCP; STAT1; HHV8GK18_gp81; UBC; VHL; TP53; FBL; PABPN1; RPS2; |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-PRMT3 (ARP40183_P050) antibody |
| Blocking Peptide |
For anti-PRMT3 (ARP40183_P050) antibody is Catalog # AAP40183 (Previous Catalog # AAPP22029) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the middle region of human PRMT3 |
| Uniprot ID |
O60678 |
| Protein Name |
Protein arginine N-methyltransferase 3 |
| Protein Accession # |
NP_005779 |
| Purification |
Affinity Purified |
| Nucleotide Accession # |
NM_005788 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
PRMT3 |
| Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit |
| Application |
WB, CHIP |
| Predicted Homology Based on Immunogen Sequence |
Cow: 86%; Dog: 85%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 86%; Rat: 100% |
| Image 1 | Human Muscle
 | WB Suggested Anti-PRMT3 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:312500
Positive Control: Human Muscle |
|
| Image 2 | HCT116
 | Quiescent human colon carcinoma HCT116 cultures were treated with 10% FBS for three time points (0, 15, 30min) or (0, 30, 60min) were used in Matrix-ChIP and real-time PCR assays at EGR1 gene (Exon1) and 15kb upstream site. |
|
