Product Number |
ARP40102_T100 |
Product Page |
www.avivasysbio.com/jmjd3-antibody-middle-region-arp40102-t100.html |
Name |
JMJD3 Antibody - middle region (ARP40102_T100) |
Protein Size (# AA) |
1643 amino acids |
Molecular Weight |
177kDa |
NCBI Gene Id |
23135 |
Host |
Rabbit |
Clonality |
Polyclonal |
Concentration |
1.0 mg/ml |
Gene Full Name |
Lysine (K)-specific demethylase 6B |
Description |
|
Alias Symbols |
JMJD3, NEDCFSA |
Peptide Sequence |
Synthetic peptide located within the following region: AGLQGVVVLEQYRTEELAQAYDAFTLVRARRARGQRRRALGQAAGTGFGS |
Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Description of Target |
JMJD3 is a histone demethylase that specifically demethylates 'Lys-27' of histone H3, thereby playing a central role in histone code. It plays a central role in regulation of posterior development, by regulating HOX gene expression. It is involved in inflammatory response by participating in macrophage differentiation in case of inflammation by regulating gene expression and macrophage differentiation. |
Protein Interactions |
WDR5; ASH2L; RBBP5; UBC; TK1; CSNK2B; HIST1H3A; WAS; SMAD3; SMAD2; SMAD4; SMAD1; |
Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
Datasheets/Manuals |
Printable datasheet for anti-KDM6B (ARP40102_T100) antibody |
Blocking Peptide |
For anti-KDM6B (ARP40102_T100) antibody is Catalog # AAP40102 (Previous Catalog # AAPP22940) |
Immunogen |
The immunogen is a synthetic peptide directed towards the middle region of human JMJD3 |
Uniprot ID |
O15054 |
Protein Name |
Lysine-specific demethylase 6B |
Protein Accession # |
AAH09994 |
Purification |
Protein A purified |
Nucleotide Accession # |
NM_001080424 |
Tested Species Reactivity |
Human |
Gene Symbol |
KDM6B |
Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit |
Application |
WB |
Predicted Homology Based on Immunogen Sequence |
Cow: 100%; Dog: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100% |
Image 1 | Human HepG2
| WB Suggested Anti-JMJD3 Antibody Titration: 1.25ug/ml Positive Control: HepG2 cell lysate |
|
Image 2 | Human Jurkat Whole Cell
| Host: Rabbit Target Name: KDM6B Sample Tissue: Human Jurkat Whole Cell Antibody Dilution: 5ug/ml |
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Image 3 | HepG2
| Host: Rabbit Target Name: JMJD3 Sample Type: HepG2 Lane A: Primary Antibody Lane B: Primary Antibody + Blocking Peptide Primary Antibody Concentration: 2.5ug/mL Peptide Concentration: 2.0ug/mL Lysate Quantity: 25ug/lane Gel Concentration: 6%-18% |
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