CREB1 Antibody - middle region (ARP39811_P050)

Data Sheet
 
Product Number ARP39811_P050
Product Page www.avivasysbio.com/creb1-antibody-middle-region-arp39811-p050.html
Name CREB1 Antibody - middle region (ARP39811_P050)
Protein Size (# AA) 341 amino acids
Molecular Weight 37kDa
NCBI Gene Id 1385
Host Rabbit
Clonality Polyclonal
Concentration 0.5 mg/ml
Gene Full Name CAMP responsive element binding protein 1
Alias Symbols CREB, CREB-1
Peptide Sequence Synthetic peptide located within the following region: TYQIRTAPTSTIAPGVVMASSPALPTQPAEEAARKREVRLMKNREAAREC
Product Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reference Mamdani,F., Am. J. Med. Genet. B Neuropsychiatr. Genet. 147B (4), 500-504
Description of Target CREB1 is a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds as a homodimer to the cAMP-responsive element, an octameric palindrome. The protein is phosphorylated by several protein kinases, and induces transcription of genes in response to hormonal stimulation of the cAMP pathway. This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds as a homodimer to the cAMP-responsive element, an octameric palindrome. The protein is phosphorylated by several protein kinases, and induces transcription of genes in response to hormonal stimulation of the cAMP pathway. Alternate splicing of this gene results in two transcript variants encoding different isoforms.
Protein Interactions UBC; NCOR1; CREM; CREBBP; RPS6KA1; NR5A2; EP300; DEAF1; TP53; CREB1; PRKG1; YAP1; MAPK14; MEIS1; DAXX; TSSK4; AKT1; ATR; SIRT1; SRA1; DR1; ATF7; GSK3B; GSK3A; ATXN3; DNMT3B; RPS6KA5; YY1; RGS13; JUN; HDAC2; HDAC1; CCDC6; PPP1CA; SUMO1; TAF4; POU2F1; MYOD1
Reconstitution and Storage For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Datasheets/Manuals Printable datasheet for anti-CREB1 (ARP39811_P050) antibody
Blocking Peptide For anti-CREB1 (ARP39811_P050) antibody is Catalog # AAP39811 (Previous Catalog # AAPP21825)
Immunogen The immunogen is a synthetic peptide directed towards the middle region of human CREB1
Uniprot ID P16220
Protein Name Cyclic AMP-responsive element-binding protein 1
Sample Type Confirmation

CREB1 is strongly supported by BioGPS gene expression data to be expressed in HT1080

There is BioGPS gene expression data showing that CREB1 is expressed in HEK293

Protein Accession # NP_604391
Purification Affinity Purified
Nucleotide Accession # NM_134442
Tested Species Reactivity Human
Gene Symbol CREB1
Predicted Species Reactivity Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Sheep, Zebrafish
Application WB
Predicted Homology Based on Immunogen Sequence Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Sheep: 100%; Zebrafish: 86%
Image 1
Human HEK293
CREB1 antibody - middle region (ARP39811_P050) validated by WB using hek293 cell lysate at 1:500.There is BioGPS gene expression data showing that CREB1 is expressed in HEK293
Image 2
Human HT1080
WB Suggested Anti-CREB1 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:62500
Positive Control: HT1080 cell lysateCREB1 is strongly supported by BioGPS gene expression data to be expressed in Human HT1080 cells
 

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