| Product Number |
ARP39753_P050 |
| Product Page |
www.avivasysbio.com/pml-antibody-middle-region-arp39753-p050.html |
| Name |
PML Antibody - middle region (ARP39753_P050) |
| Protein Size (# AA) |
882 amino acids |
| Molecular Weight |
97kDa |
| NCBI Gene Id |
5371 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
0.5 mg/ml |
| Gene Full Name |
Promyelocytic leukemia |
| Alias Symbols |
MYL, RNF71, PP8675, TRIM19 |
| Peptide Sequence |
Synthetic peptide located within the following region: TTLPPAQPAFNLQALGTYFEGLLEGPALARAEGVSTPLAGRGLAERASQQ |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reference |
Eun,B., (2008) J. Biol. Chem. 283 (9), 5939-5949 |
| Description of Target |
PML is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. PML localizes to nuclear bodies where it functions as a transcription factor an |
| Protein Interactions |
RPL11; RPL5; SUMO1; UBC; TP53; SUMO2; SUMO3; MDM2; RNF4; EGFR; NCOA2; SP100; DAXX; MAPK7; HDAC1; ATXN1; ATRX; ASF1A; EHMT2; HIRA; HTT; H3F3A; ATF7IP; PML; JAK1; EIF4E; GLIS2; UBE2I; smt3; HDAC11; HDAC6; LMNA; RNF111; CDK6; CDK2; CDK1; CASP8AP2; RBX1; SH3G |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-PML (ARP39753_P050) antibody |
| Specificity |
isoform 1, 9, 10 and 11 specific |
| Blocking Peptide |
For anti-PML (ARP39753_P050) antibody is Catalog # AAP39753 (Previous Catalog # AAPP21778) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the middle region of human PML |
| Uniprot ID |
P29590 |
| Protein Name |
Protein PML |
| Sample Type Confirmation |
There is BioGPS gene expression data showing that PML is expressed in ACHN |
| Protein Accession # |
NP_150241 |
| Purification |
Affinity Purified |
| Nucleotide Accession # |
NM_033238 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
PML |
| Predicted Species Reactivity |
Human |
| Application |
WB |
| Predicted Homology Based on Immunogen Sequence |
Human: 100% |
| Image 1 | Transfected IMR32
 | PML antibody - middle region (ARP39753_P050) validated by WB using Neuroblastoma at 1:500. |
|
| Image 2 | Human Adult Placenta
 | Host: Rabbit
Target Name: SERPINA3
Sample Type: Human Adult Placenta
Antibody Dilution: 1.0ug/ml |
|
