| Product Number |
ARP39622_P050 |
| Product Page |
www.avivasysbio.com/cbll1-antibody-n-terminal-region-arp39622-p050.html |
| Name |
CBLL1 Antibody - N-terminal region (ARP39622_P050) |
| Protein Size (# AA) |
491 amino acids |
| Molecular Weight |
54kDa |
| NCBI Gene Id |
79872 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
0.5 mg/ml |
| Gene Full Name |
Cbl proto-oncogene, E3 ubiquitin protein ligase-like 1 |
| Description |
|
| Alias Symbols |
HAKAI, RNF188 |
| Peptide Sequence |
Synthetic peptide located within the following region: MDHTDNELQGTNSSGSLGGLDVRRRIPIKLISKQANKAKPAPRTQRTINR |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reference |
Ota,T., J. Cell. Sci. 117 (PT 7), 989-998 (2004) |
| Description of Target |
Epithelial cell cadherin is endocytosed as a consequence of tyrosine phosphorylation and ubiquitination. CBLL1 is an E3 ubiquitin ligase that mediates ubiquitination of the CDH1 complex.Epithelial cell cadherin (CDH1; MIM 192090) is endocytosed as a conse |
| Protein Interactions |
DGCR6; SUMO1; UBC; CDH1; RNF2; YWHAQ; SFPQ; Cbll1; ESR1; CTTN; DOK1; SRC; CDC42; |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-CBLL1 (ARP39622_P050) antibody |
| Blocking Peptide |
For anti-CBLL1 (ARP39622_P050) antibody is Catalog # AAP39622 (Previous Catalog # AAPP21642) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the N terminal region of human CBLL1 |
| Uniprot ID |
Q75N03 |
| Protein Name |
E3 ubiquitin-protein ligase Hakai |
| Publications |
Zc3h13/Flacc is required for adenosine methylation by bridging the mRNA-binding factor Rbm15/Spenito to the m6A machinery component Wtap/Fl(2)d. Genes Dev. 32, 415-429 (2018). 29535189 |
| Protein Accession # |
NP_079090 |
| Purification |
Affinity Purified |
| Nucleotide Accession # |
NM_024814 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
CBLL1 |
| Predicted Species Reactivity |
Human, Mouse, Rat, Guinea Pig, Rabbit |
| Application |
WB |
| Predicted Homology Based on Immunogen Sequence |
Guinea Pig: 93%; Human: 100%; Mouse: 86%; Rabbit: 100%; Rat: 93% |
| Image 1 | Human COLO205
 | WB Suggested Anti-CBLL1 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:12500
Positive Control: COLO205 cell lysate |
|
