| Product Number |
ARP39513_P050 |
| Product Page |
www.avivasysbio.com/bach2-antibody-middle-region-arp39513-p050.html |
| Name |
BACH2 Antibody - middle region (ARP39513_P050) |
| Protein Size (# AA) |
841 amino acids |
| Molecular Weight |
93kDa |
| NCBI Gene Id |
60468 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
0.5 mg/ml |
| Gene Full Name |
BTB and CNC homology 1, basic leucine zipper transcription factor 2 |
| Description |
|
| Alias Symbols |
IMD60, BTBD25 |
| Peptide Sequence |
Synthetic peptide located within the following region: SGRRLEGTDPGTFSERGPPLEPRSQTVTVDFCQEMTDKCTTDEQPRKDYT |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reference |
Hong,S.W., (2008) Biochem. Biophys. Res. Commun. 365 (3), 426-432 |
| Description of Target |
BACH2 belongs to the bZIP family. It is a transcriptional regulator that acts as repressor or activator. The protein binds to Maf recognition elements (MARE) and play important roles in coordinating transcription activation and repression by MAFK. |
| Protein Interactions |
BATF3; MAFF; NFE2L3; NFE2L1; MAFG; DDIT3; COPS6; SUMO1; UBC; ARRB1; NCOR2; PATZ1; MAFK; BCL6; |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-BACH2 (ARP39513_P050) antibody |
| Blocking Peptide |
For anti-BACH2 (ARP39513_P050) antibody is Catalog # AAP39513 (Previous Catalog # AAPP23070) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the middle region of human BACH2 |
| Uniprot ID |
Q9BYV9 |
| Protein Name |
Transcription regulator protein BACH2 |
| Publications |
TBL1XR1 Mutations Drive Extranodal Lymphoma by Inducing a Pro-tumorigenic Memory Fate. Cell. 182, 297-316.e27 (2020) |
| Sample Type Confirmation |
BACH2 is supported by BioGPS gene expression data to be expressed in HEK293T |
| Protein Accession # |
NP_068585 |
| Purification |
Affinity Purified |
| Nucleotide Accession # |
NM_021813 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
BACH2 |
| Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Guinea Pig, Horse, Rabbit |
| Application |
IHC, WB |
| Predicted Homology Based on Immunogen Sequence |
Cow: 100%; Guinea Pig: 93%; Horse: 93%; Human: 100%; Mouse: 93%; Rabbit: 86%; Rat: 93% |
| Image 1 | Human Tonsil
 | Human Tonsil |
|
| Image 2 | Human 293T
 | WB Suggested Anti-BACH2 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:1562500
Positive Control: 293T cell lysateBACH2 is supported by BioGPS gene expression data to be expressed in HEK293T |
|
