| Product Number |
ARP39466_T100 |
| Product Page |
www.avivasysbio.com/nr2f2-antibody-c-terminal-region-arp39466-t100.html |
| Name |
NR2F2 Antibody - C-terminal region (ARP39466_T100) |
| Protein Size (# AA) |
414 amino acids |
| Molecular Weight |
46kDa |
| NCBI Gene Id |
7026 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
1.0 mg/ml |
| Gene Full Name |
Nuclear receptor subfamily 2, group F, member 2 |
| Alias Symbols |
ARP1, ARP-1, CHTD4, NF-E3, SRXX5, SVP40, COUPTF2, COUPTFB, TFCOUP2, COUPTFII |
| Peptide Sequence |
Synthetic peptide located within the following region: EYSCLKAIVLFTSDACGLSDVAHVESLQEKSQCALEEYVRSQYPNQPTRF |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reference |
Sato,Y., et al., (2003) J. Clin. Endocrinol. Metab. 88 (7), 3415-3420 |
| Description of Target |
NR2F2, an orphan member of the nuclear hormone receptor superfamily, acts as a transcriptional repressor by antagonizing the functions of other nuclear hormone receptors and by actively silencing transcription. However, in certain contexts, NR2F2 stimulates transcription directly. NR2F2, MyoD and p300 interact in a competitive manner, and that increasing amounts of NR2F2 have the ability to reduce the interaction between myoD and p300 invitro. NR2F2 post-transcriptionally regulates myoD activity/function, and that crosstalk between orphan nuclear receptors and the myogenic bHLH proteins has functional consequences for differentiation. |
| Protein Interactions |
NSD1; BCL11A; NR2F2; BIK; SETD7; FAM46A; HIPK3; UBC; TFAP4; Cebpb; SMARCAD1; NR2F6; POU5F1; NR3C1; PHB2; TRIP4; PIAS1; BCL11B; TRIM24; EP300; SQSTM1; HDAC1; NCOR2; MYOD1; LCK; |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-NR2F2 (ARP39466_T100) antibody |
| Blocking Peptide |
For anti-NR2F2 (ARP39466_T100) antibody is Catalog # AAP39466 (Previous Catalog # AAPP21480) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the C terminal region of human NR2F2 |
| Uniprot ID |
P24468 |
| Protein Name |
COUP transcription factor 2 |
| Publications |
Cho, K., Yi, H., Tserentsoodol, N., Searle, K. & Ferreira, P. A. Neuroprotection resulting from insufficiency of RANBP2 is associated with the modulation of protein and lipid homeostasis of functionally diverse but linked pathways in response to oxidative stress. Dis. Model. Mech. 3, 595-604 (2010). 20682751 |
| Protein Accession # |
NP_066285 |
| Purification |
Protein A purified |
| Nucleotide Accession # |
NM_021005 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
NR2F2 |
| Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Sheep, Zebrafish |
| Application |
WB |
| Predicted Homology Based on Immunogen Sequence |
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Sheep: 100%; Zebrafish: 100% |
| Image 1 | Human HepG2
 | WB Suggested Anti-NR2F2 Antibody Titration: 1.25ug/ml
ELISA Titer: 1:1562500
Positive Control: HepG2 cell lysate |
|
