Product Number |
ARP39232_P050 |
Product Page |
www.avivasysbio.com/pias1-antibody-middle-region-arp39232-p050.html |
Name |
PIAS1 Antibody - middle region (ARP39232_P050) |
Protein Size (# AA) |
651 amino acids |
Molecular Weight |
72kDa |
NCBI Gene Id |
8554 |
Host |
Rabbit |
Clonality |
Polyclonal |
Concentration |
0.5 mg/ml |
Gene Full Name |
Protein inhibitor of activated STAT, 1 |
Alias Symbols |
GBP, ZMIZ3, DDXBP1, GU/RH-II |
Peptide Sequence |
Synthetic peptide located within the following region: LPTTNGSSSGSNSSLVSSNSLRESHSHTVTNRSSTDTASIFGIIPDIISL |
Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reference |
Helbig,K.J., (2008) Antiviral Res. 77 (3), 169-176 |
Description of Target |
PIAS1 is a member of the mammalian PIAS [protein inhibitor of activated STAT-1 (signal transducer and activator of transcription-1)] family. This member contains a putative zinc-binding motif and a highly acidic region. It inhibits STAT1-mediated gene act |
Protein Interactions |
STAT1; TRIM63; TRIM55; CEP250; PRDM1; SUMO1; L3MBTL2; CBS; SHFM1; SUMO2; SUMO3; SOX2; CHUK; SPOP; YWHAZ; UBC; SKIL; SGTA; ATXN1; SMAD7; SMAD4; SMAD1; HTT; PRPF40A; PPP1CC; BARD1; PAXIP1; NR1H2; PPARGC1A; NR1H3; PPARGC1B; RAD54L2; ZMYND11; UBD; PLAG1; MYB; |
Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
Datasheets/Manuals |
Printable datasheet for anti-PIAS1 (ARP39232_P050) antibody |
Blocking Peptide |
For anti-PIAS1 (ARP39232_P050) antibody is Catalog # AAP39232 (Previous Catalog # AAPY00844) |
Immunogen |
The immunogen is a synthetic peptide directed towards the middle region of human PIAS1 |
Uniprot ID |
O75925 |
Protein Name |
E3 SUMO-protein ligase PIAS1 |
Sample Type Confirmation |
There is BioGPS gene expression data showing that PIAS1 is expressed in COLO205 |
Protein Accession # |
NP_057250 |
Purification |
Affinity Purified |
Nucleotide Accession # |
NM_016166 |
Tested Species Reactivity |
Human |
Gene Symbol |
PIAS1 |
Predicted Species Reactivity |
Human, Cow, Dog, Horse |
Application |
WB |
Predicted Homology Based on Immunogen Sequence |
Cow: 79%; Dog: 93%; Horse: 79%; Human: 100% |
Image 1 | Human U251
| Lanes: Lane 1: Untreated human U251 lysate Lane 2: IL-1beta treated human U251 lysate Primary Antibody Dilution: 1:500 Secondary Antibody: Anti-rabbit-HRP Secondary Antibody Dilution: 1:500 Gene Name: PIAS1 Submitted by: Anonymous
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Image 2 | Human COLO205
| WB Suggested Anti-PIAS1 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:312500 Positive Control: COLO205 cell lysateThere is BioGPS gene expression data showing that PIAS1 is expressed in COLO205 |
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