| Product Number |
ARP39076_P050-FITC |
| Product Page |
www.avivasysbio.com/brd4-antibody-c-terminal-region-fitc-arp39076-p050-fitc.html |
| Name |
BRD4 Antibody - C-terminal region : FITC (ARP39076_P050-FITC) |
| Protein Size (# AA) |
722 amino acids |
| Molecular Weight |
80kDa |
| Conjugation |
FITC: Fluorescein Isothiocyanate |
| NCBI Gene Id |
23476 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
0.5 mg/ml |
| Gene Full Name |
Bromodomain containing 4 |
| Alias Symbols |
CAP, MCAP, HUNK1, HUNKI |
| Peptide Sequence |
Synthetic peptide located within the following region: EIEIDFETLKPSTLRELERYVTSCLRKKRKPQAEKVDVIAGSSKMKGFSS |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer. |
| Reference |
Schweiger,M.R., (2006) J. Virol. 80 (9), 4276-4285 |
| Description of Target |
BRD4 is homologous to the murine protein MCAP, which associates with chromosomes during mitosis, and to the human RING3 protein, a serine/threonine kinase. Each of these proteins contains two bromodomains, a conserved sequence motif which may be involved in chromatin targeting.The protein encoded by this gene is homologous to the murine protein MCAP, which associates with chromosomes during mitosis, and to the human RING3 protein, a serine/threonine kinase. Each of these proteins contains two bromodomains, a conserved sequence motif which may be involved in chromatin targeting. This gene has been implicated as the chromosome 19 target of translocation t(15;19)(q13;p13.1), which defines an upper respiratory tract carcinoma in young people. Two alternatively spliced transcript variants have been described. |
| Protein Interactions |
AFF1; CDK9; CCNT1; STAT3; JMJD6; TCERG1; HEXIM1; RN7SK; PRPF40A; vif; RPL6; MYC; MLLT1; ELAVL1; SUMO2; UBC; YWHAZ; KAT8; C8orf33; MESDC2; HIST1H4A; HIST1H3A; YWHAE; MED1; EP300; KDM5B; C7orf25; CHFR; CLDN1; RFC1; RFC4; HIST2H3C; HIST2H4A; MED12; MED24; ME |
| Reconstitution and Storage |
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil). Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding. |
| Datasheets/Manuals |
Printable datasheet for anti-BRD4 (ARP39076_P050-FITC) antibody |
| Blocking Peptide |
For anti-BRD4 (ARP39076_P050-FITC) antibody is Catalog # AAP39076 (Previous Catalog # AAPS05411) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the C terminal region of human BRD4 |
| Uniprot ID |
O60885-2 |
| Protein Name |
Bromodomain-containing protein 4 |
| Protein Accession # |
NP_055114 |
| Purification |
Affinity Purified |
| Nucleotide Accession # |
NM_014299 |
| Gene Symbol |
BRD4 |
| Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit |
| Application |
CHIP, IF, WB |
| Predicted Homology Based on Immunogen Sequence |
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100% |
| Image 1 | |
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