Product Number |
ARP39018_P050-FITC |
Product Page |
www.avivasysbio.com/brd7-antibody-c-terminal-region-fitc-arp39018-p050-fitc.html |
Name |
BRD7 Antibody - C-terminal region : FITC (ARP39018_P050-FITC) |
Protein Size (# AA) |
651 amino acids |
Molecular Weight |
74kDa |
Conjugation |
FITC: Fluorescein Isothiocyanate |
NCBI Gene Id |
29117 |
Host |
Rabbit |
Clonality |
Polyclonal |
Concentration |
0.5 mg/ml |
Gene Full Name |
Bromodomain containing 7 |
Alias Symbols |
BP75, NAG4, CELTIX1 |
Peptide Sequence |
Synthetic peptide located within the following region: KELAQQVTPGDIVSTYGVRKAMGISIPSPVMENNFVDLTEDTEEPKKTDV |
Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer. |
Reference |
Zhou,J., (2004) J. Cell. Physiol. 200 (1), 89-98 |
Description of Target |
BRD7 is an activator of the Wnt signaling pathway in a DVL1-dependent manner by negatively regulating the GSK3B phosphotransferase activity. It induces dephosphorylation of GSK3B at 'Tyr-216'. |
Protein Interactions |
UBC; Dvl1; HIST2H3C; BRD2; NEFL; BARD1; LRIF1; HAP1; TFAP4; TRIM24; SUMO2; SMARCE1; SMARCD1; SMARCC2; Bcl7b; CHD7; ARID2; RBFOX2; BCL7C; SMARCC1; SMARCA4; PCBD1; POU2F1; MYC; BRCA1; BHLHE40; HIST2H4A; HIST2H3A; BTBD2; RIF1; HNRNPUL1; HIST1H2AL; AGR2; PSMD |
Reconstitution and Storage |
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil). Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding. |
Datasheets/Manuals |
Printable datasheet for anti-BRD7 (ARP39018_P050-FITC) antibody |
Blocking Peptide |
For anti-BRD7 (ARP39018_P050-FITC) antibody is Catalog # AAP39018 (Previous Catalog # AAPS03711) |
Immunogen |
The immunogen is a synthetic peptide directed towards the C terminal region of human BRD7 |
Uniprot ID |
Q9NPI1 |
Protein Name |
Bromodomain-containing protein 7 |
Sample Type Confirmation |
BRD7 is supported by BioGPS gene expression data to be expressed in Jurkat |
Protein Accession # |
NP_037395 |
Purification |
Affinity Purified |
Nucleotide Accession # |
NM_013263 |
Gene Symbol |
BRD7 |
Predicted Species Reactivity |
Human, Rat, Dog, Guinea Pig, Horse, Rabbit |
Application |
IHC, WB |
Predicted Homology Based on Immunogen Sequence |
Dog: 86%; Guinea Pig: 93%; Horse: 79%; Human: 100%; Rabbit: 79%; Rat: 86% |
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