NFATC2 Antibody - C-terminal region : FITC (ARP38988_P050-FITC)

Data Sheet
 
Product Number ARP38988_P050-FITC
Product Page www.avivasysbio.com/nfatc2-antibody-c-terminal-region-fitc-arp38988-p050-fitc.html
Name NFATC2 Antibody - C-terminal region : FITC (ARP38988_P050-FITC)
Protein Size (# AA) 925 amino acids
Molecular Weight 100kDa
Conjugation FITC: Fluorescein Isothiocyanate
NCBI Gene Id 4773
Host Rabbit
Clonality Polyclonal
Concentration 0.5 mg/ml
Gene Full Name Nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
Alias Symbols NFAT1, NFATP
Peptide Sequence Synthetic peptide located within the following region: PTVIQQQNATSQRAAKNGPPVSDQKEVLPAGVTIKQEQNLDQTYLDDVNE
Product Format Liquid. Purified antibody supplied in 1x PBS buffer.
Description of Target This gene is a member of the nuclear factor of activated T cells (NFAT) family. The product of this gene is a DNA-binding protein with a REL-homology region (RHR) and an NFAT-homology region (NHR). This protein is present in the cytosol and only translocates to the nucleus upon T cell receptor (TCR) stimulation, where it becomes a member of the nuclear factors of activated T cells transcription complex. This complex plays a central role in inducing gene transcription during the immune response. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Protein Interactions GNB2; USP22; UBC; TNPO1; CSE1L; LRRK2; IQGAP1; PPP2R1A; JUN; NFATC2; CREBBP; IRF2BP2; TFAP4; HNRNPA1; TAF9; TUBA1A; KPNB1; SUV39H1; MAPK9; MAPK8; MED31; NFATC2IP; EP300; IRF4; PPP3R1; YWHAZ; PIN1; MEF2D; FOXP3; VIM; PRKCZ; YWHAQ; EGR4; EGR1; PPP3CB;
Reconstitution and Storage All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil). Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Datasheets/Manuals Printable datasheet for anti-NFATC2 (ARP38988_P050-FITC) antibody
Blocking Peptide For anti-NFATC2 (ARP38988_P050-FITC) antibody is Catalog # AAP38988 (Previous Catalog # AAPP22972)
Immunogen The immunogen is a synthetic peptide directed towards the C terminal region of human NFATC2
Uniprot ID Q13469
Protein Name Nuclear factor of activated T-cells, cytoplasmic 2
Protein Accession # NP_775114
Purification Affinity Purified
Nucleotide Accession # NM_173091
Gene Symbol NFATC2
Predicted Species Reactivity Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish
Application IHC, WB
Predicted Homology Based on Immunogen Sequence Cow: 93%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 85%
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