Product Number |
ARP38899_T100 |
Product Page |
www.avivasysbio.com/coro1a-antibody-n-terminal-region-arp38899-t100.html |
Name |
CORO1A Antibody - N-terminal region (ARP38899_T100) |
Protein Size (# AA) |
461 amino acids |
Molecular Weight |
51kDa |
NCBI Gene Id |
11151 |
Host |
Rabbit |
Clonality |
Polyclonal |
Concentration |
1.0 mg/ml |
Gene Full Name |
Coronin, actin binding protein, 1A |
Description |
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Alias Symbols |
p57, IMD8, TACO, CLABP, HCORO1, CLIPINA |
Peptide Sequence |
Synthetic peptide located within the following region: MSRQVVRSSKFRHVFGQPAKADQCYEDVRVSQTTWDSGFCAVNPKFVALI |
Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reference |
Anand,P.K. (2005) FEMS Microbiol. Lett. 250 (1), 137-144 |
Description of Target |
CORO1A is a novel actin-binding protein with a WD repeat and a leucine zipper motif. CORO1A forms homodimers, that the association is mediated by the leucine zipper structure in the C-terminal region, and that it plays a role in the cross-linking of F-actin in the cell. The leukocyte plasma membrane associates with the actin cytoskeleton through CORO1A.Downregulation of CORO1A gene transcription restricts entry/survival of mycobacteria within macrophages |
Protein Interactions |
FSD2; GOLGA2; UBC; YTHDC1; SPATA20; POT1; TAB1; GIT2; POLR1C; STAT3; SMARCD1; MAGOH; SMAD3; LMO2; FHL3; FMNL1; NCF4; THBS1; ACTB; DKK1; UBE2G2; |
Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
Datasheets/Manuals |
Printable datasheet for anti-CORO1A (ARP38899_T100) antibody |
Blocking Peptide |
For anti-CORO1A (ARP38899_T100) antibody is Catalog # AAP38899 (Previous Catalog # AAPY00708) |
Immunogen |
The immunogen is a synthetic peptide directed towards the N terminal region of human CORO1A |
Uniprot ID |
Q2YD73 |
Protein Name |
Coronin-1A |
Publications |
Differential proteomic analysis of tibial subchondral bone from male and female guinea pigs with spontaneous osteoarthritis. Exp Ther Med. 21, 633 (2021) 33968164 |
Sample Type Confirmation |
CORO1A is supported by BioGPS gene expression data to be expressed in Jurkat |
Protein Accession # |
NP_009005 |
Purification |
Protein A purified |
Nucleotide Accession # |
NM_007074 |
Tested Species Reactivity |
Human |
Gene Symbol |
CORO1A |
Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish |
Application |
WB |
Predicted Homology Based on Immunogen Sequence |
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 86% |
Image 1 | Human Jurkat
| WB Suggested Anti-CORO1A Antibody Titration: 2.5ug/ml ELISA Titer: 1:312500 Positive Control: Jurkat cell lysateCORO1A is supported by BioGPS gene expression data to be expressed in Jurkat |
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