CREB3 Antibody - middle region (ARP38790_P050)

Data Sheet
 
Product Number ARP38790_P050
Product Page www.avivasysbio.com/creb3-antibody-middle-region-arp38790-p050.html
Name CREB3 Antibody - middle region (ARP38790_P050)
Protein Size (# AA) 371 amino acids
Molecular Weight 41kDa
NCBI Gene Id 10488
Host Rabbit
Clonality Polyclonal
Concentration 0.5 mg/ml
Gene Full Name CAMP responsive element binding protein 3
Alias Symbols LZIP, LUMAN, sLZIP
Peptide Sequence Synthetic peptide located within the following region: PPLEWPFPDLFSEPLCRGPILPLQANLTRKGGWLPTGSPSVILQDRYSG
Product Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reference Mamdani,F., (er) Am. J. Med. Genet. B Neuropsychiatr. Genet. (2008) In press
Description of Target CREB3 is a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds to the cAMP-responsive element, an octameric palindrome. The protein interacts with host cell factor C1, which also associates with the herpes simplex virus (HSV) protein VP16 that induces transcription of HSV immediate-early genes. This protein and VP16 both bind to the same site on host cell factor C1. It is thought that the interaction between this protein and host cell factor C1 plays a role in the establishment of latency during HSV infection. An additional transcript variant has been identified, but its biological validity has not been determined. This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds to the cAMP-responsive element, an octameric palindrome. The protein interacts with host cell factor C1, which also associates with the herpes simplex virus (HSV) protein VP16 that induces transcription of HSV immediate-early genes. This protein and VP16 both bind to the same site on host cell factor C1. It is thought that the interaction between this protein and host cell factor C1 plays a role in the establishment of latency during HSV infection. An additional transcript variant has been identified, but its biological validity has not been determined. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Protein Interactions COPS5; HCFC1; JUN; CREB3L1; CREB3L3; CREB3; NFE2L3; NFE2L2; DDIT3; CEBPG; ATF4; ATF3; TTLL5; RRAS2; OS9; RABAC1; SQLE; BCAT2; CLP1; UBC; HDAC3; MALL; NFIL3; APPBP2; STX8; BNIP2; CCR1; EMD;
Reconstitution and Storage For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Datasheets/Manuals Printable datasheet for anti-CREB3 (ARP38790_P050) antibody
Blocking Peptide For anti-CREB3 (ARP38790_P050) antibody is Catalog # AAP38790 (Previous Catalog # AAPP20995)
Immunogen The immunogen is a synthetic peptide directed towards the middle region of human CREB3
Uniprot ID O43889
Protein Name Cyclic AMP-responsive element-binding protein 3
Protein Accession # NP_006359
Purification Affinity Purified
Nucleotide Accession # NM_006368
Tested Species Reactivity Human
Gene Symbol CREB3
Predicted Species Reactivity Human, Cow, Dog
Application WB
Predicted Homology Based on Immunogen Sequence Cow: 80%; Dog: 80%; Human: 100%
Image 1
Human HepG2
WB Suggested Anti-CREB3 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:312500
Positive Control: HepG2 cell lysate
 

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