SAP30 Antibody - middle region (ARP38393_T100)

Data Sheet
 
Product Number ARP38393_T100
Product Page www.avivasysbio.com/sap30-antibody-middle-region-arp38393-t100.html
Name SAP30 Antibody - middle region (ARP38393_T100)
Protein Size (# AA) 220 amino acids
Molecular Weight 23kDa
Subunit SAP30
NCBI Gene Id 8819
Host Rabbit
Clonality Polyclonal
Concentration 1.0 mg/ml
Gene Full Name Sin3A-associated protein, 30kDa
Alias Symbols -
Peptide Sequence Synthetic peptide located within the following region: YQLQVNTLRRYKRHFKLPTRPGLNKAQLVEIVGCHFRSIPVNEKDTLTYF
Product Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reference Sironi,E., (2004) J. Cutan. Pathol. 31 (4), 318-322
Description of Target Histone acetylation plays a key role in the regulation of eukaryotic gene expression. Histone acetylation and deacetylation are catalyzed by multisubunit complexes. SAP30 is a component of the histone deacetylase complex, which includes SIN3, SAP18, HDAC1, HDAC2, RbAp46, RbAp48, and other polypeptides. This complex is active in deacetylating core histone octamers, but inactive in deacetylating nucleosomal histones.Histone acetylation plays a key role in the regulation of eukaryotic gene expression. Histone acetylation and deacetylation are catalyzed by multisubunit complexes. The protein encoded by this gene is a component of the histone deacetylase complex, which includes SIN3, SAP18, HDAC1, HDAC2, RbAp46, RbAp48, and other polypeptides. This complex is active in deacetylating core histone octamers, but inactive in deacetylating nucleosomal histones. A pseudogene of this gene is located on chromosome 3.
Protein Interactions HDAC3; CUL4B; DDB1; HDAC1; SIN3A; UBC; HDAC2; BRMS1L; ING1; ARID4A; SAMSN1; ZNF395; UBASH3B; RBBP7; RBBP4; CHD4; ALL1; TAF6; SMARCA2; SAP25; RBP1; HIST2H2BE; PCBD1; ID3; SAP30BP; HIST2H4A; HBP1; HIST1H2AL; BRMS1; CIR1; HIST3H3; NCOR1; NCOR2; MXD1; YY1; HT
Reconstitution and Storage For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Datasheets/Manuals Printable datasheet for anti-SAP30 (ARP38393_T100) antibody
Blocking Peptide For anti-SAP30 (ARP38393_T100) antibody is Catalog # AAP38393 (Previous Catalog # AAPP20579)
Immunogen The immunogen is a synthetic peptide directed towards the middle region of human SAP30
Uniprot ID O75446
Protein Name Histone deacetylase complex subunit SAP30
Protein Accession # NP_003855
Purification Protein A purified
Nucleotide Accession # NM_003864
Tested Species Reactivity Human
Gene Symbol SAP30
Predicted Species Reactivity Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish
Application WB
Predicted Homology Based on Immunogen Sequence Cow: 100%; Dog: 93%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 79%
Image 1
Transfected 293T
WB Suggested Anti-SAP30 Antibody Titration: 1.25ug/ml
ELISA Titer: 1:312500
Positive Control: Transfected 293T
 

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