Product Number |
ARP38393_T100 |
Product Page |
www.avivasysbio.com/sap30-antibody-middle-region-arp38393-t100.html |
Name |
SAP30 Antibody - middle region (ARP38393_T100) |
Protein Size (# AA) |
220 amino acids |
Molecular Weight |
23kDa |
Subunit |
SAP30 |
NCBI Gene Id |
8819 |
Host |
Rabbit |
Clonality |
Polyclonal |
Concentration |
1.0 mg/ml |
Gene Full Name |
Sin3A-associated protein, 30kDa |
Alias Symbols |
- |
Peptide Sequence |
Synthetic peptide located within the following region: YQLQVNTLRRYKRHFKLPTRPGLNKAQLVEIVGCHFRSIPVNEKDTLTYF |
Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reference |
Sironi,E., (2004) J. Cutan. Pathol. 31 (4), 318-322 |
Description of Target |
Histone acetylation plays a key role in the regulation of eukaryotic gene expression. Histone acetylation and deacetylation are catalyzed by multisubunit complexes. SAP30 is a component of the histone deacetylase complex, which includes SIN3, SAP18, HDAC1, HDAC2, RbAp46, RbAp48, and other polypeptides. This complex is active in deacetylating core histone octamers, but inactive in deacetylating nucleosomal histones.Histone acetylation plays a key role in the regulation of eukaryotic gene expression. Histone acetylation and deacetylation are catalyzed by multisubunit complexes. The protein encoded by this gene is a component of the histone deacetylase complex, which includes SIN3, SAP18, HDAC1, HDAC2, RbAp46, RbAp48, and other polypeptides. This complex is active in deacetylating core histone octamers, but inactive in deacetylating nucleosomal histones. A pseudogene of this gene is located on chromosome 3. |
Protein Interactions |
HDAC3; CUL4B; DDB1; HDAC1; SIN3A; UBC; HDAC2; BRMS1L; ING1; ARID4A; SAMSN1; ZNF395; UBASH3B; RBBP7; RBBP4; CHD4; ALL1; TAF6; SMARCA2; SAP25; RBP1; HIST2H2BE; PCBD1; ID3; SAP30BP; HIST2H4A; HBP1; HIST1H2AL; BRMS1; CIR1; HIST3H3; NCOR1; NCOR2; MXD1; YY1; HT |
Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
Datasheets/Manuals |
Printable datasheet for anti-SAP30 (ARP38393_T100) antibody |
Blocking Peptide |
For anti-SAP30 (ARP38393_T100) antibody is Catalog # AAP38393 (Previous Catalog # AAPP20579) |
Immunogen |
The immunogen is a synthetic peptide directed towards the middle region of human SAP30 |
Uniprot ID |
O75446 |
Protein Name |
Histone deacetylase complex subunit SAP30 |
Protein Accession # |
NP_003855 |
Purification |
Protein A purified |
Nucleotide Accession # |
NM_003864 |
Tested Species Reactivity |
Human |
Gene Symbol |
SAP30 |
Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish |
Application |
WB |
Predicted Homology Based on Immunogen Sequence |
Cow: 100%; Dog: 93%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 79% |
Image 1 | Transfected 293T
| WB Suggested Anti-SAP30 Antibody Titration: 1.25ug/ml ELISA Titer: 1:312500 Positive Control: Transfected 293T |
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