| Product Number |
ARP38383_P050 |
| Product Page |
www.avivasysbio.com/edf1-antibody-middle-region-arp38383-p050.html |
| Name |
EDF1 Antibody - middle region (ARP38383_P050) |
| Protein Size (# AA) |
148 amino acids |
| Molecular Weight |
16kDa |
| NCBI Gene Id |
8721 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
0.5 mg/ml |
| Gene Full Name |
Endothelial differentiation-related factor 1 |
| Alias Symbols |
MBF1, EDF-1, CFAP280 |
| Peptide Sequence |
Synthetic peptide located within the following region: INEKPQVIADYESGRAIPNNQVLGKIERAIGLKLRGKDIGKPIEKGPRAK |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reference |
Bolognese,F., Gene 374, 87-95 (2006) |
| Description of Target |
EDF1 encodes a protein that may regulate endothelial cell differentiation. It has been postulated that the protein functions as a bridging molecule that interconnects regulatory proteins and the basal transcriptional machinery, thereby modulating the transcription of genes involved in endothelial differentiation. This protein has also been found to act as a transcriptional coactivator by interconnecting the general transcription factor TATA element-binding protein (TBP) and gene-specific activators. Two alternatively spliced transcripts which encode distinct proteins have been found for this gene. This gene encodes a protein that may regulate endothelial cell differentiation. It has been postulated that the protein functions as a bridging molecule that interconnects regulatory proteins and the basal transcriptional machinery, thereby modulating the transcription of genes involved in endothelial differentiation. This protein has also been found to act as a transcriptional coactivator by interconnecting the general transcription factor TATA element-binding protein (TBP) and gene-specific activators. Two alternatively spliced transcripts which encode distinct proteins have been found for this gene. |
| Protein Interactions |
MEOX2; UBC; IDH3G; UBE2I; MAPK6; NRL; JUN; CEBPA; NR1H3; NR5A2; PPARG; TBP; TAF1; NR5A1; RXRA; PRKCA; ATF2; CREB1; ATF1; CALM3; CALM1; |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-EDF1 (ARP38383_P050) antibody |
| Blocking Peptide |
For anti-EDF1 (ARP38383_P050) antibody is Catalog # AAP38383 (Previous Catalog # AAPP20569) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the middle region of human EDF1 |
| Uniprot ID |
O60869 |
| Protein Name |
Endothelial differentiation-related factor 1 |
| Protein Accession # |
NP_003783 |
| Purification |
Affinity Purified |
| Nucleotide Accession # |
NM_003792 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
EDF1 |
| Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse |
| Application |
IF, IHC, WB |
| Predicted Homology Based on Immunogen Sequence |
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 93%; Rat: 100% |
| Image 1 | Human Prostate
 | Immunohistochemistry with Prostate tissue at an antibody concentration of 5ug/ml using anti-EDF1 antibody (ARP38383_P050) |
|
| Image 2 | Human Fibroblasts
 | Sample Type : Fibroblasts
|
|
| Image 3 | Human brain
 | WB Suggested Anti-EDF1 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:312500
Positive Control: Human brain |
|
