HMGA2 Antibody - N-terminal region (ARP38356_T100)

• Product Number: ARP38356_T100
• Name: HMGA2 Antibody - N-terminal region (ARP38356_T100)
• Protein Size (# AA): 109 amino acids
• Molecular Weight: 12kDa
• NCBI Gene Id: 8091
• Host: Rabbit
• Clonality: Polyclonal
• Concentration: 1.0 mg/ml
• Gene Full Name: High mobility group AT-hook 2
• Alias Symbols: BABL, LIPO, SRS5, HMGIC, HMGI-C, STQTL9
• Peptide Sequence: Synthetic peptide located within the following region: PSTSAQGQPAAPAPQKRGRGRPRKQQQEPTGEPSPKRPRGRPKGSKNKSP
• Product Format: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Reference: Kubo,T., (2006) Biochem. Biophys. Res. Commun. 340 (2), 476-481
• Description of Target: HMGA2 belongs to the non-histone chromosomal high mobility group (HMG) protein family. HMG proteins function as architectural factors and are essential components of the enhancesome. This protein contains structural DNA-binding domains and may act as a transcriptional regulating factor. It may be play a role in adipogenesis, mesenchymal differentiation and diet-induced obesity.This gene encodes a protein that belongs to the non-histone chromosomal high mobility group (HMG) protein family. HMG proteins function as architectural factors and are essential components of the enhancesome. This protein contains structural DNA-binding domains and may act as a transcriptional regulating factor. Identification of the deletion, amplification, and rearrangement of this gene that are associated with myxoid liposarcoma suggests a role in adipogenesis and mesenchymal differentiation. A gene knock out study of the mouse counterpart demonstrated that this gene is involved in diet-induced obesity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
• Protein Interactions: PSIP1; SYNCRIP; PTBP1; PCBP2; PA2G4; NPM1; XRCC6; APEX1; HDGF; UBC; PRKCA; SMAD9; SMAD5; SMAD1; PRMT6; RB1; PIAS3; SMAD3; RELA; NFKB1; CDK1; CSNK2A2; CSNK2A1;
• Reconstitution and Storage: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
• Blocking Peptide: For anti-HMGA2 (ARP38356_T100) antibody is Catalog # AAP38356 (Previous Catalog # AAPP20543)
• Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human HMGA2
• Uniprot ID: P52926
• Protein Name: High mobility group protein HMGI-C
• Sample Type Confirmation:

  HMGA2 is supported by BioGPS gene expression data to be expressed in HEK293T

• Protein Accession #: NP_003474
• Purification: Protein A purified
• Nucleotide Accession #: NM_003483
• Tested Species Reactivity: Human
• Gene Symbol: HMGA2
• Predicted Species Reactivity: Human, Mouse, Rat, Cow, Dog, Goat, Guinea Pig, Horse, Rabbit, Yeast, Zebrafish
• Application: WB
• Predicted Homology Based on Immunogen Sequence: Cow: 100%; Dog: 100%; Goat: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Yeast: 92%; Zebrafish: 100%
• Image 1: Human 293T
  
  Lanes:
  Lane 1: 5 ug 293T cell lysate
  Lane 2: 10 ug 293T cell lysate
  Lane 3: 20 ug 293T cell lysate
  Primary Antibody Dilution:
  1:1000
  Secondary Antibody:
  Anti-rabbit HRP
  Secondary Antibody Dilution:
  1:10000
  Gene Name:
  HMGA2
  Submitted by:
  Anonymous
  HMGA2 is supported by BioGPS gene expression data to be expressed in HEK293T