IRF4 Antibody - N-terminal region (ARP38154_P050)

Data Sheet
 
Product Number ARP38154_P050
Product Page www.avivasysbio.com/irf4-antibody-n-terminal-region-arp38154-p050.html
Name IRF4 Antibody - N-terminal region (ARP38154_P050)
Protein Size (# AA) 451 amino acids
Molecular Weight 52 kDa
NCBI Gene Id 3662
Host Rabbit
Clonality Polyclonal
Concentration 0.5 mg/ml
Gene Full Name Interferon regulatory factor 4
Alias Symbols MUM1, LSIRF, SHEP8, NF-EM5
Peptide Sequence Synthetic peptide located within the following region: MNLEGGGRGGEFGMSAVSCGNGKLRQWLIDQIDSGKYPGLVWENEEKSIF
Product Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reference Lehtonen,A., (2005) J. Immunol. 175 (10), 6570-6579
Description of Target IFN regulatory factor (IRF)-4 is a lymphoid/myeloid-restricted member of the IRF transcription factor family that plays an essential role in the homeostasis and function of mature lymphocytes. IRF-4 expression is tightly regulated in resting primary T cells and is transiently induced at the mRNA and protein levels after activation by Ag-mimetic stimuli such as TCR cross-linking or treatment with phorbol ester and calcium ionophore (PMA/ionomycin).
Protein Interactions UBC; STAT6; BCL6; TOP1; IRAK1; PRRC2B; YTHDC2; VPS35; PEG10; TLK2; CARM1; IKBKAP; ETV7; BATF; HOXB13; PROX1; HOXC11; FKBP4; SPIB; PRDM1; MYD88; TRAF2; NFATC2; SPI1;
Reconstitution and Storage For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Enhanced Validation
Relative Expression (Western Blot) Avivasheild
Datasheets/Manuals Printable datasheet for anti-IRF4 (ARP38154_P050) antibody
Additional Information WB Information: Jurkat cell lysate. Antibody concentration: 0.5 ug/ml. Gel concentration: 12%.
Blocking Peptide For anti-IRF4 (ARP38154_P050) antibody is Catalog # AAP38154 (Previous Catalog # AAPS04906)
Immunogen The immunogen is a synthetic peptide directed towards the N terminal region of human IRF4
Uniprot ID Q15306
Protein Name Interferon regulatory factor 4
Protein Accession # NP_002451
Purification Affinity Purified
Nucleotide Accession # NM_002460
Tested Species Reactivity Human
Gene Symbol IRF4
Predicted Species Reactivity Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish
Application WB
Predicted Homology Based on Immunogen Sequence Cow: 100%; Dog: 93%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 93%; Rat: 100%; Zebrafish: 86%
Image 1
Human Skin
Human Skin
Image 2
Western Blot
25 ug of the indicated Human whole cell extracts was loaded onto a 12% SDS-PAGE gel. 1 ug/mL of the antibody was used in this experiment.
 

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