Product Number |
ARP38154_P050 |
Product Page |
www.avivasysbio.com/irf4-antibody-n-terminal-region-arp38154-p050.html |
Name |
IRF4 Antibody - N-terminal region (ARP38154_P050) |
Protein Size (# AA) |
451 amino acids |
Molecular Weight |
52 kDa |
NCBI Gene Id |
3662 |
Host |
Rabbit |
Clonality |
Polyclonal |
Concentration |
0.5 mg/ml |
Gene Full Name |
Interferon regulatory factor 4 |
Alias Symbols |
MUM1, LSIRF, SHEP8, NF-EM5 |
Peptide Sequence |
Synthetic peptide located within the following region: MNLEGGGRGGEFGMSAVSCGNGKLRQWLIDQIDSGKYPGLVWENEEKSIF |
Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reference |
Lehtonen,A., (2005) J. Immunol. 175 (10), 6570-6579 |
Description of Target |
IFN regulatory factor (IRF)-4 is a lymphoid/myeloid-restricted member of the IRF transcription factor family that plays an essential role in the homeostasis and function of mature lymphocytes. IRF-4 expression is tightly regulated in resting primary T cells and is transiently induced at the mRNA and protein levels after activation by Ag-mimetic stimuli such as TCR cross-linking or treatment with phorbol ester and calcium ionophore (PMA/ionomycin). |
Protein Interactions |
UBC; STAT6; BCL6; TOP1; IRAK1; PRRC2B; YTHDC2; VPS35; PEG10; TLK2; CARM1; IKBKAP; ETV7; BATF; HOXB13; PROX1; HOXC11; FKBP4; SPIB; PRDM1; MYD88; TRAF2; NFATC2; SPI1; |
Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
Enhanced Validation |
Relative Expression (Western Blot) |
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Datasheets/Manuals |
Printable datasheet for anti-IRF4 (ARP38154_P050) antibody |
Additional Information |
WB Information: Jurkat cell lysate. Antibody concentration: 0.5 ug/ml. Gel concentration: 12%. |
Blocking Peptide |
For anti-IRF4 (ARP38154_P050) antibody is Catalog # AAP38154 (Previous Catalog # AAPS04906) |
Immunogen |
The immunogen is a synthetic peptide directed towards the N terminal region of human IRF4 |
Uniprot ID |
Q15306 |
Protein Name |
Interferon regulatory factor 4 |
Protein Accession # |
NP_002451 |
Purification |
Affinity Purified |
Nucleotide Accession # |
NM_002460 |
Tested Species Reactivity |
Human |
Gene Symbol |
IRF4 |
Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish |
Application |
WB |
Predicted Homology Based on Immunogen Sequence |
Cow: 100%; Dog: 93%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 93%; Rat: 100%; Zebrafish: 86% |
Image 1 | Human Skin
| Human Skin |
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Image 2 | Western Blot
| 25 ug of the indicated Human whole cell extracts was loaded onto a 12% SDS-PAGE gel. 1 ug/mL of the antibody was used in this experiment. |
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