| Product Number |
ARP38094_T100-Biotin |
| Product Page |
www.avivasysbio.com/foxo1a-antibody-n-terminal-region-biotin-arp38094-t100-biotin.html |
| Name |
FOXO1A Antibody - N-terminal region : Biotin (ARP38094_T100-Biotin) |
| Protein Size (# AA) |
655 amino acids |
| Molecular Weight |
70kDa |
| Conjugation |
Biotin |
| NCBI Gene Id |
2308 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
0.5 mg/ml |
| Gene Full Name |
Forkhead box O1 |
| Alias Symbols |
FKH1, FKHR, FOXO1A |
| Peptide Sequence |
Synthetic peptide located within the following region: MAEAPQVVEIDPDFEPLPRPRSCTWPLPRPEFSQSNSATSSPAPSGSAAA |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer. |
| Reference |
Okamoto,H., et al., (2006) J. Clin. Invest. 116 (3), 775-782 |
| Description of Target |
FOXO1A belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. The specific function of FOXO1A has not yet been determined; however, it may play a role in myogenic growth and differentiation. Translocation of FOXO1A gene with PAX3 has been associated with alveolar rhabdomyosarcoma. |
| Protein Interactions |
EP300; AKT1; MST1; SIRT1; FHL2; ATG7; IRF3; FSHR; ESR1; Ubc; TXNRD1; RARA; MDM2; NLK; SKP2; SIRT2; STUB1; CREBBP; PML; LRPPRC; HOXA11; HNF4A; PARP1; DYRK1A; THRB; CSNK1G1; YWHAG; GSK3B; SMAD3; PAK1; PPARG; YWHAZ; SMAD4; AR; G6PC; SRC; CEBPB; FOXG1; HOXA10 |
| Reconstitution and Storage |
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil). Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding. |
| Datasheets/Manuals |
Printable datasheet for anti-FOXO1 (ARP38094_T100-Biotin) antibody |
| Blocking Peptide |
For anti-FOXO1 (ARP38094_T100-Biotin) antibody is Catalog # AAP38094 (Previous Catalog # AAPP20268) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the N terminal region of human FOXO1A |
| Uniprot ID |
Q12778 |
| Protein Name |
Forkhead box protein O1 |
| Publications |
Hsu, C.-Y. & Hu, T.-H. Energy-regulated molecules maintain young status in the trophocytes and fat cells of old queen honeybees. Biogerontology 15, 389-400 (2014). WB, Human, Pig, Bovine, Dog, Rat, Yeast, Mouse 24973265 |
| Protein Accession # |
NP_002006 |
| Nucleotide Accession # |
NM_002015 |
| Gene Symbol |
FOXO1 |
| Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Pig, Yeast |
| Application |
WB |
| Predicted Homology Based on Immunogen Sequence |
Cow: 92%; Dog: 92%; Human: 100%; Mouse: 85%; Pig: 92%; Rat: 85%; Yeast: 85% |
| Image 1 | |
|
