| Product Number |
ARP38044_P050 |
| Product Page |
www.avivasysbio.com/tada2l-antibody-n-terminal-region-arp38044-p050.html |
| Name |
TADA2L Antibody - N-terminal region (ARP38044_P050) |
| Protein Size (# AA) |
305 amino acids |
| Molecular Weight |
36kDa |
| NCBI Gene Id |
6871 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
0.5 mg/ml |
| Gene Full Name |
Transcriptional adaptor 2A |
| Alias Symbols |
ADA2, ADA2A, KL04P, hADA2, TADA2L |
| Peptide Sequence |
Synthetic peptide located within the following region: MDRLGPFSNDPSDKPPCRGCSSYLMEPYIKCAECGPPPFFLCLQCFTRGF |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reference |
Yang,M., (2008) Cancer Biol. Ther. 7 (1), 120-128 |
| Description of Target |
Many DNA-binding transcriptional activator proteins enhance the initiation rate of RNA polymerase II-mediated gene transcription by interacting functionally with the general transcription machinery bound at the basal promoter. Adaptor proteins are usually required for this activation, possibly to acetylate and destabilize nucleosomes, thereby relieving chromatin constraints at the promoter. TADA2L is a transcriptional activator adaptor and has been found to be part of the PCAF histone acetylase complex.Many DNA-binding transcriptional activator proteins enhance the initiation rate of RNA polymerase II-mediated gene transcription by interacting functionally with the general transcription machinery bound at the basal promoter. Adaptor proteins are usually required for this activation, possibly to acetylate and destabilize nucleosomes, thereby relieving chromatin constraints at the promoter. The protein encoded by this gene is a transcriptional activator adaptor and has been found to be part of the PCAF histone acetylase complex. Two transcript variants encoding different isoforms have been identified for this gene. |
| Protein Interactions |
MFAP1; MAGOH; KPNA2; FBF1; PRPF31; PPP1R16B; ZFYVE26; SF3A3; FARS2; MTX2; EIF4E2; FAM127C; KLHL38; TTC9C; ZNF564; TEKT4; LOC149950; KLC4; TTC23; GPSM3; CDCA7L; C1orf109; CCHCR1; PRKAB2; ARNT2; USP22; TADA3; HNF4A; LYN; HSP90AA1; KAT2B; MCPH1; PAXIP1; SUPT |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-TADA2A (ARP38044_P050) antibody |
| Blocking Peptide |
For anti-TADA2A (ARP38044_P050) antibody is Catalog # AAP38044 (Previous Catalog # AAPP20219) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the N terminal region of human TADA2L |
| Uniprot ID |
Q9BVJ0 |
| Protein Name |
Transcriptional adapter 2-alpha |
| Sample Type Confirmation |
TADA2A is strongly supported by BioGPS gene expression data to be expressed in 721_B, Jurkat |
| Protein Accession # |
NP_597683 |
| Purification |
Affinity Purified |
| Nucleotide Accession # |
NM_133439 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
TADA2A |
| Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit |
| Application |
WB |
| Predicted Homology Based on Immunogen Sequence |
Cow: 86%; Dog: 93%; Guinea Pig: 93%; Horse: 93%; Human: 100%; Mouse: 93%; Rabbit: 93%; Rat: 93% |
| Image 1 | Human Jurkat
 | WB Suggested Anti-TADA2L Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:312500
Positive Control: Jurkat cell lysate.TADA2A is strongly supported by BioGPS gene expression data to be expressed in Jurkat |
|
| Image 2 | Human 721_B
 | Host: Rabbit
Target Name: TADA2A
Sample Type: 721_B
Antibody Dilution: 1.0ug/mlTADA2A is strongly supported by BioGPS gene expression data to be expressed in Human 721_B cells |
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