Product Number |
ARP36693_P050 |
Product Page |
www.avivasysbio.com/mcm7-antibody-n-terminal-region-arp36693-p050.html |
Name |
MCM7 Antibody - N-terminal region (ARP36693_P050) |
Protein Size (# AA) |
389 amino acids |
Molecular Weight |
42kDa |
NCBI Gene Id |
4176 |
Host |
Rabbit |
Clonality |
Polyclonal |
Concentration |
0.5 mg/ml |
Gene Full Name |
minichromosome maintenance complex component 7 |
Alias Symbols |
MCM2, CDC47, P85MCM, P1CDC47, PNAS146, PPP1R104, P1.1-MCM3 |
Peptide Sequence |
Synthetic peptide located within the following region: KYGNQLVRLAHREQVALYVDLDDVAEDDPELVDSICENARRYAKLFADAV |
Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Description of Target |
MCM7 encodes a protein that is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 6 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. Cyclin D1-dependent kinase, CDK4, is found to associate with this protein, and may regulate the binding of this protein with the tumorsuppressor protein RB1/RB. |
Protein Interactions |
AK8; MIPOL1; C8orf34; USHBP1; MCMBP; CCDC102B; TRIM54; MBIP; UBQLN1; TRIM27; NAB2; KIFC3; GOLGA2; PNMA1; UBC; SP2; HAUS2; CEP250; CEP57; SUMO2; SUMO3; PCNA; STAU1; SUZ12; RNF2; MCM4; MCM2; HSP90AB1; PRMT1; PRRC1; CLUH; TOMM34; TRIM16; HYOU1; BAG3; MIB1; P |
Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
Datasheets/Manuals |
Printable datasheet for anti-MCM7 (ARP36693_P050) antibody |
Blocking Peptide |
For anti-MCM7 (ARP36693_P050) antibody is Catalog # AAP36693 |
Immunogen |
The immunogen is a synthetic peptide directed towards the N-terminal region of Human MCM7 |
Uniprot ID |
P33993-2 |
Protein Name |
DNA replication licensing factor MCM7 |
Protein Accession # |
NP_877577 |
Purification |
Affinity Purified |
Nucleotide Accession # |
NM_182776 |
Tested Species Reactivity |
Human |
Gene Symbol |
MCM7 |
Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish |
Application |
WB |
Predicted Homology Based on Immunogen Sequence |
Cow: 86%; Dog: 86%; Guinea Pig: 93%; Horse: 79%; Human: 100%; Mouse: 93%; Rabbit: 93%; Rat: 100%; Zebrafish: 93% |
Image 1 | Human Thyroid Tumor
| Host: Rabbit Target Name: MCM7 Sample Type: Thyroid Tumor lysates Antibody Dilution: 1.0ug/ml |
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