Product Number |
ARP36600_T100 |
Product Page |
www.avivasysbio.com/gjb1-antibody-c-terminal-region-arp36600-t100.html |
Name |
GJB1 Antibody - C-terminal region (ARP36600_T100) |
Protein Size (# AA) |
283 amino acids |
Molecular Weight |
31kDa |
NCBI Gene Id |
2705 |
Host |
Rabbit |
Clonality |
Polyclonal |
Concentration |
1.0 mg/ml |
Gene Full Name |
Gap junction protein, beta 1, 32kDa |
Alias Symbols |
CMTX, CX32, CMTX1 |
Peptide Sequence |
Synthetic peptide located within the following region: GFGHRLSPEYKQNEINKLLSEQDGSLKDILRRSPGTGAGLAEKSDRCSAC |
Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reference |
Dagli,M.L., et al., (2004) Carcinogenesis 25 (4), 483-492 |
Description of Target |
This gene encodes for a Connexin 32 protein. A large Charcot-Marie-Tooth disease family has been identified with a novel mutation in the Cx32 P2 promoter region at position -526bp. Cx32 mutants that are associated with a CNS phenotype may have toxic effects in oligodendrocytes. |
Protein Interactions |
UBC; VKORC1; APP; CNST; OCLN; PRKACA; SRC; PRKCA; GJB2; CALM1; CAV1; JUP; |
Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
Datasheets/Manuals |
Printable datasheet for anti-GJB1 (ARP36600_T100) antibody |
Blocking Peptide |
For anti-GJB1 (ARP36600_T100) antibody is Catalog # AAP36600 (Previous Catalog # AAPP07839) |
Immunogen |
The immunogen is a synthetic peptide directed towards the C terminal region of human GJB1 |
Uniprot ID |
P08034 |
Protein Name |
Gap junction beta-1 protein |
Publications |
Hu, Z. et al. Quantitative liver-specific protein fingerprint in blood: a signature for hepatotoxicity. Theranostics 4, 215-28 (2014). 24465277 |
Protein Accession # |
NP_000157 |
Purification |
Protein A purified |
Nucleotide Accession # |
NM_000166 |
Tested Species Reactivity |
Human, Mouse |
Gene Symbol |
GJB1 |
Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit |
Application |
IHC, WB |
Predicted Homology Based on Immunogen Sequence |
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100% |
Image 1 | HepG2, Human lung
| Host: Rabbit Target: GJB1 Positive control (+): HepG2 (HG) Negative control (-): Human lung (LU) Antibody concentration: 2.5ug/ml |
|
Image 2 | Mouse Spleen
| Host: Mouse Target Name: GJB1 Sample Tissue: Mouse Spleen Antibody Dilution: 1ug/ml |
|
Image 3 | Human Jurkat
| WB Suggested Anti-GJB1 Antibody Titration: 2.5ug/ml ELISA Titer: 1:312500 Positive Control: Jurkat cell lysate |
|
Image 4 | Human Intestine
| Human Intestine |
|