| Product Number |
ARP36365_T100 |
| Product Page |
www.avivasysbio.com/ddx5-antibody-c-terminal-region-arp36365-t100.html |
| Name |
DDX5 Antibody - C-terminal region (ARP36365_T100) |
| Protein Size (# AA) |
614 amino acids |
| Molecular Weight |
68kDa |
| NCBI Gene Id |
1655 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
1.0 mg/ml |
| Gene Full Name |
DEAD (Asp-Glu-Ala-Asp) box helicase 5 |
| Alias Symbols |
p68, HLR1, G17P1, HUMP68 |
| Peptide Sequence |
Synthetic peptide located within the following region: SFGSNFVSAGIQTSFRTGNPTGTYQNGYDSTQQYGSNVPNMHNGMNQQAY |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reference |
Guil,S., et al., (2003) Mol. Cell. Biol. 23 (8), 2927-2941 |
| Description of Target |
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. DDX5 encodes a DEAD box protein, which is a RNA-dependent ATPase, and also a proliferation-associated nuclear antigen, specifically reacting with the simian virus 40 tumor antigen. DDX5 consists of 13 exons, and alternatively spliced transcripts containing several intron sequences have been detected, but no isoforms encoded by these transcripts have been identified. |
| Protein Interactions |
FUS; ESR1; DROSHA; MAPKAPK2; UBC; TP53; TUBGCP3; AURKB; SPRTN; AURKA; SUMO2; SUMO3; MDM2; CEP250; STAU1; RPA3; RPA2; RPA1; EED; EZH2; RNF2; SUZ12; rev; DDX17; PABPC4; PRPSAP1; PIN1; LRSAM1; FKBP10; ERO1L; DBNL; WDR4; PARK2; FBXO6; MAPK10; SP1; TARDBP; UBD |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-DDX5 (ARP36365_T100) antibody |
| Blocking Peptide |
For anti-DDX5 (ARP36365_T100) antibody is Catalog # AAP36365 (Previous Catalog # AAPP08424) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the C terminal region of human DDX5 |
| Uniprot ID |
P17844 |
| Protein Name |
Probable ATP-dependent RNA helicase DDX5 |
| Publications |
Laux, A. et al. Localization of endogenous morphine-like compounds in the mouse spinal cord. J. Comp. Neurol. 520, 1547-61 (2012). 22174317
The zebrafish miR-462/miR-731 cluster is induced under hypoxic stress via hypoxia-inducible factor 1a and functions in cellular adaptations. FASEB J. 29, 4901-13 (2015). 26265472 |
| Sample Type Confirmation |
DDX5 is supported by BioGPS gene expression data to be expressed in Jurkat |
| Protein Accession # |
NP_004387 |
| Purification |
Protein A purified |
| Nucleotide Accession # |
NM_004396 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
DDX5 |
| Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit |
| Application |
WB |
| Predicted Homology Based on Immunogen Sequence |
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100% |
| Image 1 | Human Jurkat
 | WB Suggested Anti-DDX5 Antibody Titration: 1.25ug/ml
ELISA Titer: 1:1562500
Positive Control: Jurkat cell lysateDDX5 is supported by BioGPS gene expression data to be expressed in Jurkat |
|
