FUBP1 Antibody - middle region (ARP35704_P050)

Data Sheet
 
Product Number ARP35704_P050
Product Page www.avivasysbio.com/fubp1-antibody-middle-region-arp35704-p050.html
Name FUBP1 Antibody - middle region (ARP35704_P050)
Protein Size (# AA) 644 amino acids
Molecular Weight 67kDa
NCBI Gene Id 8880
Host Rabbit
Clonality Polyclonal
Concentration 0.5 mg/ml
Gene Full Name Far upstream element (FUSE) binding protein 1
Alias Symbols FBP, FUBP, hDH V
Peptide Sequence Synthetic peptide located within the following region: YYAHYYQQQAQPPPAAPAGAPTTTQTNGQGDQQNPAPAGQVDYTKAWEEY
Product Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reference Ewing,R.M., Mol. Syst. Biol. 3, 89 (2007)
Description of Target FUBP1 is a ssDNA binding protein that activates the far upstream element (FUSE) of c-myc and stimulates expression of c-myc in undifferentiated cells. Regulation of FUSE by FUBP occurs through single-strand binding of FUBP to the non-coding strand. This protein has been shown to function as an ATP-dependent DNA helicase.This gene encodes a ssDNA binding protein that activates the far upstream element (FUSE) of c-myc and stimulates expression of c-myc in undifferentiated cells. Regulation of FUSE by FUBP occurs through single-strand binding of FUBP to the non-coding strand. This protein has been shown to function as an ATP-dependent DNA helicase. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Protein Interactions UBC; MDM2; EED; DDX19A; NSUN2; PLD3; ARPC2; ACTR2; ACTR3; ARPC4; HIST1H2BO; SH3GL1; RPA1; PPP5C; LGALS1; CNN2; BAG1; ACO1; AARSD1; GRPEL1; NIF3L1; RPRD1B; CD81; ITGA4; FN1; ATF2; AIMP2; VCAM1; DHX36; MRPL32; MRPL38; MRPL41; MRPL2; CERS2; MRPL42; MRPL46; P
Reconstitution and Storage For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Datasheets/Manuals Printable datasheet for anti-FUBP1 (ARP35704_P050) antibody
Blocking Peptide For anti-FUBP1 (ARP35704_P050) antibody is Catalog # AAP35704 (Previous Catalog # AAPP23552)
Immunogen The immunogen is a synthetic peptide directed towards the middle region of human FUBP1
Uniprot ID Q96AE4
Protein Name Far upstream element-binding protein 1
Publications

Milosevic, J., Bulau, P., Mortz, E. & Eickelberg, O. Subcellular fractionation of TGF-beta1-stimulated lung epithelial cells: a novel proteomic approach for identifying signaling intermediates. Proteomics 9, 1230-40 (2009). 19253281

Sample Type Confirmation

FUBP1 is strongly supported by BioGPS gene expression data to be expressed in HepG2

Protein Accession # NP_003893
Purification Affinity Purified
Nucleotide Accession # NM_003902
Tested Species Reactivity Human
Gene Symbol FUBP1
Predicted Species Reactivity Human, Mouse, Rat, Cow, Dog, Guinea Pig, Rabbit
Application IHC, WB
Predicted Homology Based on Immunogen Sequence Cow: 100%; Dog: 100%; Guinea Pig: 93%; Human: 100%; Mouse: 92%; Rabbit: 100%; Rat: 100%
Image 1
Human Breast
Immunohistochemistry with Human Breast tissue at an antibody concentration of 5.0ug/ml using anti-FUBP1 antibody (ARP35704_P050)
Image 2
Human HepG2
WB Suggested Anti-FUBP1 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:1562500
Positive Control: HepG2 cell lysateFUBP1 is strongly supported by BioGPS gene expression data to be expressed in Human HepG2 cells
 

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