Product Number |
ARP35695_P050 |
Product Page |
www.avivasysbio.com/edf1-antibody-n-terminal-region-arp35695-p050.html |
Name |
EDF1 Antibody - N-terminal region (ARP35695_P050) |
Protein Size (# AA) |
148 amino acids |
Molecular Weight |
16kDa |
NCBI Gene Id |
8721 |
Host |
Rabbit |
Clonality |
Polyclonal |
Concentration |
0.5 mg/ml |
Gene Full Name |
Endothelial differentiation-related factor 1 |
Alias Symbols |
MBF1, EDF-1, CFAP280 |
Peptide Sequence |
Synthetic peptide located within the following region: MAESDWDTVTVLRKKGPTAAQAKSKQAILAAQRRGEDVETSKKWAAGQNK |
Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reference |
Bolognese,F., Gene 374, 87-95 (2006) |
Description of Target |
EDF1 encodes a protein that may regulate endothelial cell differentiation. It has been postulated that the protein functions as a bridging molecule that interconnects regulatory proteins and the basal transcriptional machinery, thereby modulating the tran |
Protein Interactions |
MEOX2; UBC; IDH3G; UBE2I; MAPK6; NRL; JUN; CEBPA; NR1H3; NR5A2; PPARG; TBP; TAF1; NR5A1; RXRA; PRKCA; ATF2; CREB1; ATF1; CALM3; CALM1; |
Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
Datasheets/Manuals |
Printable datasheet for anti-EDF1 (ARP35695_P050) antibody |
Blocking Peptide |
For anti-EDF1 (ARP35695_P050) antibody is Catalog # AAP35695 (Previous Catalog # AAPP23549) |
Immunogen |
The immunogen is a synthetic peptide directed towards the N terminal region of human EDF1 |
Uniprot ID |
O60869 |
Protein Name |
Endothelial differentiation-related factor 1 |
Publications |
Leidi, M., Mariotti, M. & Maier, J. A. M. EDF-1 contributes to the regulation of nitric oxide release in VEGF-treated human endothelial cells. Eur. J. Cell Biol. 89, 654-60 (2010). 20605058
Leidi, M., Mariotti, M. & Maier, J. A. M. The effects of silencing EDF-1 in human endothelial cells. Atherosclerosis 211, 55-60 (2010). 20185128
Leidi, M., Mariotti, M. & Maier, J. A. M. Transcriptional coactivator EDF-1 is required for PPARgamma-stimulated adipogenesis. Cell. Mol. Life Sci. 66, 2733-42 (2009). 19554257 |
Protein Accession # |
NP_003783 |
Purification |
Affinity Purified |
Nucleotide Accession # |
NM_003792 |
Tested Species Reactivity |
Human |
Gene Symbol |
EDF1 |
Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Zebrafish |
Application |
IF, WB |
Predicted Homology Based on Immunogen Sequence |
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rat: 100%; Zebrafish: 79% |
Image 1 | Human THP-1
| WB Suggested Anti-EDF1 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:1562500 Positive Control: THP-1 cell lysate |
|
Image 2 | human fibroblasts
| WB Suggested Anti-GPD1 Antibody Titration: 5 ug/ml Positive Control: HG |
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