CLCN6 Antibody - C-terminal region : FITC (ARP35334_T100-FITC)

Data Sheet
 
Product Number ARP35334_T100-FITC
Product Page www.avivasysbio.com/clcn6-antibody-c-terminal-region-fitc-arp35334-t100-fitc.html
Name CLCN6 Antibody - C-terminal region : FITC (ARP35334_T100-FITC)
Protein Size (# AA) 353 amino acids
Molecular Weight 39kDa
Conjugation FITC: Fluorescein Isothiocyanate
NCBI Gene Id 1185
Host Rabbit
Clonality Polyclonal
Concentration 0.5 mg/ml
Gene Full Name Chloride channel, voltage-sensitive 6
Alias Symbols CLC-6, CONRIBA
Peptide Sequence Synthetic peptide located within the following region: PQFQSISLRKIQFNFPYFRSDRDKRDFVSAGAAAGVAAAFGAPIGGTLFS
Product Format Liquid. Purified antibody supplied in 1x PBS buffer.
Reference Tran,P., et al., (2002) Mamm. Genome 13 (9), 483-492
Description of Target The CLCN family of voltage-dependent chloride channel genes comprises nine members (CLCN1-7, Ka and Kb) which demonstrate quite diverse functional characteristics while sharing significant sequence homology. Chloride channel 6 and 7 belong to a subbranch of this family. Chloride channel 6 has four different alternatively spliced transcript variants. This gene is in close vicinity to two other kidney-specific chloride channel genes, CLCNKA and CLCNKB.
Protein Interactions UBC; PPP2R1A;
Reconstitution and Storage All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil). Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Datasheets/Manuals Printable datasheet for anti-CLCN6 (ARP35334_T100-FITC) antibody
Blocking Peptide For anti-CLCN6 (ARP35334_T100-FITC) antibody is Catalog # AAP35334 (Previous Catalog # AAPP07254)
Immunogen The immunogen is a synthetic peptide directed towards the C terminal region of human CLCN6
Uniprot ID Q5SNX3
Protein Name Chloride transport protein 6
Publications

Jensen, V. K. et al. A quantitative assay for lysosomal acidification rates in human osteoclasts. Assay Drug Dev. Technol. 9, 157-64 (2011). WB, Mouse, Rat, Bovine, Dog, Pig, Horse, Rabbit, Guinea pig, Human 21050068

Protein Accession # NP_068504
Nucleotide Accession # NM_021736
Gene Symbol CLCN6
Predicted Species Reactivity Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit
Application WB
Predicted Homology Based on Immunogen Sequence Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%
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